Age and education correction of mini-mental state examination for english- and spanish-speaking elderly

Dan M Mungas, S. C. Marshall, M. Weldon, M. Haan, Bruce R Reed

Research output: Contribution to journalArticle

251 Citations (Scopus)

Abstract

Previous research has shown that the Mini-Mental State Examination (MMS) is biased as a measure of cognitive impairment in minority and low-education patients. The purpose of this study was to (1) develop a statistical correction for effects of age and education and (2) test the efficacy of the statistically adjusted MMS (MMSAdj) as a screening test for dementia using different ethnic groups and education levels. We used a population-based community survey sample (n = 590) composed of 46.6% Hispanics and 53.4% non- Hispanics to derive the statistical correction, defined as: MMSAdj = Raw MMS · (0.471 x [Education-12]) + (0.131 x [Age-70]). Ethnicity and language of test administration were not significantly related to MMSAdj in the community survey sample, but the raw MMS was strongly influenced by these factors. We used an independent sample (n = 2,983) of patients evaluated through the California Alzheimer's Disease Diagnostic and Treatment Centers to test the diagnostic accuracy of the MMS and the MMSAdj across low- and high-education groups and across whites, Hispanics, and blacks. Results showed greater stability of sensitivity and specificity across education levels and ethnic groups for the MMSAdj than for the raw MMS and suggest that the MMSAdj is a preferable measure of cognitive impairment for low-education and minority individuals.

Original languageEnglish (US)
Pages (from-to)700-706
Number of pages7
JournalNeurology
Volume46
Issue number3
StatePublished - Mar 1996

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Education
Hispanic Americans
Ethnic Groups
Language Tests
Patient Education
Routine Diagnostic Tests
Dementia
Alzheimer Disease
Sensitivity and Specificity
Research
Population
Cognitive Dysfunction
Surveys and Questionnaires
Therapeutics

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Age and education correction of mini-mental state examination for english- and spanish-speaking elderly. / Mungas, Dan M; Marshall, S. C.; Weldon, M.; Haan, M.; Reed, Bruce R.

In: Neurology, Vol. 46, No. 3, 03.1996, p. 700-706.

Research output: Contribution to journalArticle

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