Abstract
In the clinical management of acute and chronic cardiac dysfunction, systemic vasodilators constitute a new approach through their reduction of elevated left ventricular wall tension during systole (ventricular afterload) by decreasing aortic impedance and/or diminishing venous return to the heart. Thus the agents may result in elevation of lowered cardiac output by reducing peripheral vascular resistance and/or in decline of increased ventricular end-diastolic volume (ventricular preload) by lowering venous tone. In addition, these agents cause concomitant reduction in myocardial oxygen requirements which is of special importance in ischemic heart disease.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 199-204 |
| Number of pages | 6 |
| Journal | Advances in Cardiology |
| Volume | Vol.22 |
| State | Published - 1977 |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Afterload reduction in congestive heart failure. / Miller, R. R.; Awan, N.; Amsterdam, Ezra A; Mason, D. T.
In: Advances in Cardiology, Vol. Vol.22, 1977, p. 199-204.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Afterload reduction in congestive heart failure
AU - Miller, R. R.
AU - Awan, N.
AU - Amsterdam, Ezra A
AU - Mason, D. T.
PY - 1977
Y1 - 1977
N2 - In the clinical management of acute and chronic cardiac dysfunction, systemic vasodilators constitute a new approach through their reduction of elevated left ventricular wall tension during systole (ventricular afterload) by decreasing aortic impedance and/or diminishing venous return to the heart. Thus the agents may result in elevation of lowered cardiac output by reducing peripheral vascular resistance and/or in decline of increased ventricular end-diastolic volume (ventricular preload) by lowering venous tone. In addition, these agents cause concomitant reduction in myocardial oxygen requirements which is of special importance in ischemic heart disease.
AB - In the clinical management of acute and chronic cardiac dysfunction, systemic vasodilators constitute a new approach through their reduction of elevated left ventricular wall tension during systole (ventricular afterload) by decreasing aortic impedance and/or diminishing venous return to the heart. Thus the agents may result in elevation of lowered cardiac output by reducing peripheral vascular resistance and/or in decline of increased ventricular end-diastolic volume (ventricular preload) by lowering venous tone. In addition, these agents cause concomitant reduction in myocardial oxygen requirements which is of special importance in ischemic heart disease.
UR - http://www.scopus.com/inward/record.url?scp=0017761846&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0017761846&partnerID=8YFLogxK
M3 - Article
C2 - 413334
AN - SCOPUS:0017761846
VL - Vol.22
SP - 199
EP - 204
JO - Advances in Cardiology
JF - Advances in Cardiology
SN - 0065-2326
ER -