Adverse Reactions to Vaccination. From Anaphylaxis to Autoimmunity

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Abstract

Vaccines are important for providing protection from infectious diseases. Vaccination initiates a process that stimulates development of a robust and long-lived immune response to the disease agents in the vaccine. Side effects are sometimes associated with vaccination. These vary from development of acute hypersensitivity responses to vaccine components to local tissue reactions that are annoying but not significantly detrimental to the patient. The pathogenesis of these responses and the consequent clinical outcomes are discussed. Overstimulation of the immune response and the potential relationship to autoimmunity is evaluated in relation to genetic predisposition.

Original languageEnglish (US)
JournalVeterinary Clinics of North America - Small Animal Practice
DOIs
StateAccepted/In press - Jan 1 2017

Fingerprint

anaphylaxis
autoimmunity
Anaphylaxis
Autoimmunity
Vaccination
Vaccines
vaccination
vaccines
immune response
Genetic Predisposition to Disease
hypersensitivity
infectious diseases
Communicable Diseases
Hypersensitivity
pathogenesis
adverse effects

Keywords

  • Anaphylaxis
  • Arthus reaction
  • Autoimmunity
  • IgE
  • Vaccine reactions

ASJC Scopus subject areas

  • Small Animals

Cite this

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