Adverse clinical outcomes associated with elevated blood alcohol levels at the time of burn injury

Geoffrey M. Silver, Joslyn M. Albright, Carol R. Schermer, Marcia Halerz, Peggie Conrad, Paul D. Ackerman, Linda Lau, Mary Ann Emanuele, Elizabeth J. Kovacs, Richard L. Gamelli

Research output: Contribution to journalArticle

49 Scopus citations

Abstract

Elevated blood alcohol content (BAC) on admission is associated with poorer outcomes, larger burns and more inhalation injury. This study's purpose was to examine the effects of alcohol through a matched case-controlled study, measuring early and extended markers of clinical outcomes. The hypothesis was that patients with an elevated admission BAC would require more resuscitation and have a longer hospital stay. Admissions 16 to 75 years of age with 15 to 75% TBSA and admission BACs were identified. Patients with BAC >30 mg/dl (BAC+, cases) were matched with patients with undetectable BAC (BAC-, controls), according to age, sex, TBSA, inhalation injury and mechanism. Screening identified 258 patients, 146 with admission BACs. Twenty-seven had a BAC ≥ 30 mg/dl. There were 24 matched pairs. At 24 hours, BAC+ group had larger acute physiology and chronic health evaluation II scores (23.33 vs 18.75, P < .05), fluid requirements (5.25 vs 3.82 L (cc/kg/ TBSA), P < .05), and base deficit (11.15 vs 7.15, P < .05). The duration of mechanical ventilation (14.85 vs 4.23 days, P < .05), intensive care unit length of stay (22.85 vs 9.38, P < .05), hospital length of stay (28.95 vs 15.68, P < .05), and mean hospital charges ($239,507 vs $144,598, P < .05) were increased in the BAC+ patients. Despite matched baseline injury characteristics, elevated BAC was associated with poorer short term and extended clinical outcomes, illustrating the impact of alcohol intoxication on physiologic derangement after burn injury.

Original languageEnglish (US)
Pages (from-to)784-789
Number of pages6
JournalJournal of Burn Care and Research
Volume29
Issue number5
DOIs
StatePublished - Sep 2008
Externally publishedYes

ASJC Scopus subject areas

  • Emergency Medicine
  • Rehabilitation
  • Surgery

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    Silver, G. M., Albright, J. M., Schermer, C. R., Halerz, M., Conrad, P., Ackerman, P. D., Lau, L., Emanuele, M. A., Kovacs, E. J., & Gamelli, R. L. (2008). Adverse clinical outcomes associated with elevated blood alcohol levels at the time of burn injury. Journal of Burn Care and Research, 29(5), 784-789. https://doi.org/10.1097/BCR.0b013e31818481bc