Advances in Management of Atopic Dermatitis: New Therapies and Novel Uses of Existing Treatments

Elizabeth P. Chase, April W. Armstrong

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Atopic dermatitis (AD) is a chronic inflammatory skin condition marked by intensely pruritic, eczematous changes. First-line therapy includes topical corticosteroids during an exacerbation and long-term emollient use, followed by topical calcineurin inhibitors, phototherapy, and systemic therapy in more difficult cases. The need for more effective AD therapies with safer side effect profiles has pushed researchers to devise new therapies and to recycle traditional treatments for use in a novel manner. Innovative therapies include barrier therapy, novel antistaphylococcal treatments, new immunomodulatory agents, unconventional antipruritic agents, exclusionary diets, and probiotics. Advancements in these options have paved the way for a targeted approach to AD therapy. We will review the latest clinical research exploring these cutting-edge AD treatment modalities and discuss forward-thinking therapy strategies that use conventional AD medications in a novel manner.

Original languageEnglish (US)
Pages (from-to)17-24
Number of pages8
JournalSeminars in Cutaneous Medicine and Surgery
Volume31
Issue number1
DOIs
StatePublished - Mar 2012

Keywords

  • Atopic dermatitis
  • Barrier cream
  • Biologics
  • Drug
  • Eczema
  • Medication
  • Proactive therapy
  • Systemic
  • Therapy
  • Topical
  • Treatment

ASJC Scopus subject areas

  • Dermatology
  • Surgery

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