Advanced Monte Carlo simulations of emission tomography imaging systems with GATE

David Sarrut, Mateusz Bała, Manuel Bardi s, Julien Bert, Maxime Chauvin, Konstantinos Chatzipapas, Mathieu Dupont, Ane Etxebeste, Louise M. Fanchon, Sébastien Jan, Gunjan Kayal, Assen S. Kirov, Paweł Kowalski, Wojciech Krzemien, Joey Labour, Mirjam Lenz, George Loudos, Brahim Mehadji, Laurent Ménard, Christian MorelPanagiotis Papadimitroulas, Magdalena Rafecas, Julien Salvadori, Daniel Seiter, Mariele Stockhoff, Etienne Testa, Carlotta Trigila, Uwe Pietrzyk, Stefaan Vandenberghe, Marc Antoine Verdier, Dimitris Visvikis, Karl Ziemons, Milan Zvolský, Emilie Roncali

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Built on top of the Geant4 toolkit, GATE is collaboratively developed for more than 15 years to design Monte Carlo simulations of nuclear-based imaging systems. It is, in particular, used by researchers and industrials to design, optimize, understand and create innovative emission tomography systems. In this paper, we reviewed the recent developments that have been proposed to simulate modern detectors and provide a comprehensive report on imaging systems that have been simulated and evaluated in GATE. Additionally, some methodological developments that are not specific for imaging but that can improve detector modeling and provide computation time gains, such as Variance Reduction Techniques and Artificial Intelligence integration, are described and discussed.

Original languageEnglish (US)
Article number10TR03
JournalPhysics in medicine and biology
Issue number10
StatePublished - May 21 2021


  • Compton Camera
  • Monte Carlo simulation
  • Positron emission tomography
  • Single-photon emission computed tomography

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging


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