Adult cockatiels (Nymphicus hollandicus) at maintenance are more sensitive to diets containing excess vitamin A than to vitamin A-deficient diets

Elizabeth A. Koutsos, Lisa A Tell, Leslie Woods, Kirk C. Klasing

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

The purpose of this experiment was to examine the physiological responses of adult cockatiels at maintenance to dietary vitamin A (VA) concentrations, and to identify concentrations associated with deficiency and toxicity. Adult cockatiels at maintenance (n = 22, 2-3 y of age) were fed a diet of 0, 600, 3000 or 30,000 μg VA/kg (0, 2000, 10,000 or 100,000 IU), and monitored for signs of VA deficiency or toxicity for up to 706 d. The analyzed diet concentrations were 0, 835, 2815 and 24,549 μg/kg, respectively. After 269 d, birds fed the 30,000 μg/kg VA diet had greater plasma retinal concentrations, markedly intensified vocalization patterns, pancreatitis and multifocal accumulation of lymphocytes in the lamina propria of the duodenum compared to birds fed the 600 μg/kg diet (P < 0.05). The 3000 μg/kg VA diet induced increased plasma retinol, splenic hemosiderosis and altered vocalization patterns (P < 0.05), although not as striking as those induced by the 30,000 μg/kg VA diet. The secondary antibody response was reduced after 225 d and vocalization patterns were altered in birds fed 0 μg/kg VA (P < 0.05), but after almost 2 y there were no changes in body condition, plasma retinol, organ pathology or classical signs of deficiency such as squamous metaplasia of nasal epithelia. Thus, adult cockatiels at maintenance were more susceptible to VA toxicity than to VA deficiency and concentrations ≥ 3000 μg VA/kg diet can cause toxicity. It is possible that disturbances in VA nutrition contribute to the widespread incidence of behavioral problems reported in companion birds.

Original languageEnglish (US)
Pages (from-to)1898-1902
Number of pages5
JournalJournal of Nutrition
Volume133
Issue number6
StatePublished - Jun 1 2003

Keywords

  • Cockatiel
  • Deficiency
  • Requirement
  • Toxicity
  • Vitamin A

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science

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