Adjuvant metronomic chemotherapy in a dog with nasal transitional carcinoma

Hyung Jin Park, Ja Won Kim, Seong Mok Jeong, Ho Jung Choi, Hwa Young Son, Kun Ho Song, Kyoung Won Seo

Research output: Contribution to journalArticlepeer-review


A four-year-old spayed female Maltese dog weighing 3 kg was referred with reverse sneezing and fourmonth history of unilateral nasal discharge. She was diagnosed as nasal transitional carcinoma which in bilateral nasal cavity and extending into the frontal sinus by biopsy with rhinoscopy. Metronomic chemotherapy with cyclophosphamide (12.5 mg/m2) and toceranib phosphate (2.5 mg/kg) was initiated following after surgical treatment of nasal mass debulking. Clinical response was good and had no side effects during the chemotherapy period (11 months after diagnosis). This is a case report describing adjuvant metronomic chemotherapy in nasal transitional carcinoma in Korea.

Original languageEnglish (US)
Pages (from-to)183-186
Number of pages4
JournalJournal of Veterinary Clinics
Issue number2
StatePublished - Jan 1 2015
Externally publishedYes


  • Cyclophosphamide
  • Metronomic chemotherapy
  • Nasal transitional carcinoma
  • Surgical debulking
  • Toceranib

ASJC Scopus subject areas

  • veterinary(all)


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