Adenoviral infection in captive moose (Alces alces) in Canada

Catherine M. Shilton, Dale A. Smith, Leslie Woods, Graham J. Crawshaw, Howard D. Lehmkuhl

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Adenoviral infection was associated with hemorrhagic enteritis, serosal hemorrhages, and severe pulmonary edema in six captive moose (Alces alces) in Toronto, Ontario, Canada: an adult female moose and three calves in 1985 and two calves in 1998. Adenoviral disease was suspected based on histological findings of systemic vasculitis and widespread thrombosis associated with amphophilic intranuclear inclusions in endothelial cells. Diagnosis was confirmed by immunohistochemistry using antiserum to bovine adenovirus type 5, transmission electron microscopic identification of viral particles consistent in morphology with adenovirus within nuclei of pulmonary endothelial cells in an affected calf, and virus isolation. The restriction pattern of virus isolated from the lung of one of the calves indicated that the virus was identical to a recently characterized adenovirus in black-tailed deer (Odocoileus hemionus) in California. The moose adenovirus reported here may have been endemic in the captive moose herd, or infection may have resulted from either direct or indirect contact with other species of captive or wild cervids. This is the first report of adenoviral infection in moose and of the presence of adenoviral disease in a cervid in Canada.

Original languageEnglish (US)
Pages (from-to)73-79
Number of pages7
JournalJournal of Zoo and Wildlife Medicine
Volume33
Issue number1
StatePublished - 2002
Externally publishedYes

Fingerprint

Alces alces
Adenoviridae
Canada
virus
Viruses
Infection
calves
infection
Odocoileus hemionus
Endothelial Cells
lungs
Intranuclear Inclusion Bodies
Systemic Vasculitis
Lung
viruses
deer
endothelial cells
Deer
Enteritis
Ontario

Keywords

  • Adenovirus
  • Alces alces
  • Enteritis
  • Moose
  • Vasculitis

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Environmental Science(all)
  • veterinary(all)

Cite this

Shilton, C. M., Smith, D. A., Woods, L., Crawshaw, G. J., & Lehmkuhl, H. D. (2002). Adenoviral infection in captive moose (Alces alces) in Canada. Journal of Zoo and Wildlife Medicine, 33(1), 73-79.

Adenoviral infection in captive moose (Alces alces) in Canada. / Shilton, Catherine M.; Smith, Dale A.; Woods, Leslie; Crawshaw, Graham J.; Lehmkuhl, Howard D.

In: Journal of Zoo and Wildlife Medicine, Vol. 33, No. 1, 2002, p. 73-79.

Research output: Contribution to journalArticle

Shilton, CM, Smith, DA, Woods, L, Crawshaw, GJ & Lehmkuhl, HD 2002, 'Adenoviral infection in captive moose (Alces alces) in Canada', Journal of Zoo and Wildlife Medicine, vol. 33, no. 1, pp. 73-79.
Shilton, Catherine M. ; Smith, Dale A. ; Woods, Leslie ; Crawshaw, Graham J. ; Lehmkuhl, Howard D. / Adenoviral infection in captive moose (Alces alces) in Canada. In: Journal of Zoo and Wildlife Medicine. 2002 ; Vol. 33, No. 1. pp. 73-79.
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