Adaptive optics - Optical coherence tomography for in vivo retinal imaging: Effects of spectral bandwidth on image quality

Robert Zawadzki, Steven M. Jones, Mingtao Zhao, Stacey S. Choi, Sophie S. Laut, Scot S. Olivier, Joseph A. Izatt, John S Werner

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Adaptive Optics - Optical Coherence Tomography (AO-OCT) has demonstrated a promising improvement in lateral resolution for retinal imaging compared to standard OCT. Recent developments in Fourier-domain OCT technology allow AO-OCT instruments to acquire three-dimensional (3D) retinal structures with high speed and high "volumetric" resolution (in all three dimensions). One of the most important factors (besides acquisition speed) that will determine the true potential of this technique is its ability to achieve diffraction-limited lateral resolution (∼3 μn) while operating in the ultrahigh axial resolution range (∼3 μn) offered by OCT. Theoretical studies have shown that the eye's chromatic aberrations may drastically reduce volumetric resolution. This is a critical finding because for "standard" stand alone ultrahigh OCT, increasing the spectral bandwidth of the light source improves axial resolution without compromising lateral resolution. To study the effects of spectral bandwidth on AO-OCT systems for retinal imaging two different light sources offering 6 and 3 μn axial resolution were tested. This comparison was based on both AO correcting system performance as well as the quality of corresponding OCT images.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume6138
DOIs
StatePublished - 2006
EventOphthalmic Technologies XVI - San Jose, CA, United States
Duration: Jan 21 2006Jan 24 2006

Other

OtherOphthalmic Technologies XVI
CountryUnited States
CitySan Jose, CA
Period1/21/061/24/06

Fingerprint

Adaptive optics
Optical tomography
Image quality
Bandwidth
Imaging techniques
Light sources
Aberrations
Diffraction

Keywords

  • Aberration compensation
  • Adaptive optics
  • Medical optics instrumentation
  • Ophthalmology
  • Optical coherence tomography

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Zawadzki, R., Jones, S. M., Zhao, M., Choi, S. S., Laut, S. S., Olivier, S. S., ... Werner, J. S. (2006). Adaptive optics - Optical coherence tomography for in vivo retinal imaging: Effects of spectral bandwidth on image quality. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 6138). [61381X] https://doi.org/10.1117/12.647540

Adaptive optics - Optical coherence tomography for in vivo retinal imaging : Effects of spectral bandwidth on image quality. / Zawadzki, Robert; Jones, Steven M.; Zhao, Mingtao; Choi, Stacey S.; Laut, Sophie S.; Olivier, Scot S.; Izatt, Joseph A.; Werner, John S.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6138 2006. 61381X.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Zawadzki, R, Jones, SM, Zhao, M, Choi, SS, Laut, SS, Olivier, SS, Izatt, JA & Werner, JS 2006, Adaptive optics - Optical coherence tomography for in vivo retinal imaging: Effects of spectral bandwidth on image quality. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 6138, 61381X, Ophthalmic Technologies XVI, San Jose, CA, United States, 1/21/06. https://doi.org/10.1117/12.647540
Zawadzki R, Jones SM, Zhao M, Choi SS, Laut SS, Olivier SS et al. Adaptive optics - Optical coherence tomography for in vivo retinal imaging: Effects of spectral bandwidth on image quality. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6138. 2006. 61381X https://doi.org/10.1117/12.647540
Zawadzki, Robert ; Jones, Steven M. ; Zhao, Mingtao ; Choi, Stacey S. ; Laut, Sophie S. ; Olivier, Scot S. ; Izatt, Joseph A. ; Werner, John S. / Adaptive optics - Optical coherence tomography for in vivo retinal imaging : Effects of spectral bandwidth on image quality. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6138 2006.
@inproceedings{237e13aecfb844719c82321f59486aa9,
title = "Adaptive optics - Optical coherence tomography for in vivo retinal imaging: Effects of spectral bandwidth on image quality",
abstract = "Adaptive Optics - Optical Coherence Tomography (AO-OCT) has demonstrated a promising improvement in lateral resolution for retinal imaging compared to standard OCT. Recent developments in Fourier-domain OCT technology allow AO-OCT instruments to acquire three-dimensional (3D) retinal structures with high speed and high {"}volumetric{"} resolution (in all three dimensions). One of the most important factors (besides acquisition speed) that will determine the true potential of this technique is its ability to achieve diffraction-limited lateral resolution (∼3 μn) while operating in the ultrahigh axial resolution range (∼3 μn) offered by OCT. Theoretical studies have shown that the eye's chromatic aberrations may drastically reduce volumetric resolution. This is a critical finding because for {"}standard{"} stand alone ultrahigh OCT, increasing the spectral bandwidth of the light source improves axial resolution without compromising lateral resolution. To study the effects of spectral bandwidth on AO-OCT systems for retinal imaging two different light sources offering 6 and 3 μn axial resolution were tested. This comparison was based on both AO correcting system performance as well as the quality of corresponding OCT images.",
keywords = "Aberration compensation, Adaptive optics, Medical optics instrumentation, Ophthalmology, Optical coherence tomography",
author = "Robert Zawadzki and Jones, {Steven M.} and Mingtao Zhao and Choi, {Stacey S.} and Laut, {Sophie S.} and Olivier, {Scot S.} and Izatt, {Joseph A.} and Werner, {John S}",
year = "2006",
doi = "10.1117/12.647540",
language = "English (US)",
isbn = "0819461814",
volume = "6138",
booktitle = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

}

TY - GEN

T1 - Adaptive optics - Optical coherence tomography for in vivo retinal imaging

T2 - Effects of spectral bandwidth on image quality

AU - Zawadzki, Robert

AU - Jones, Steven M.

AU - Zhao, Mingtao

AU - Choi, Stacey S.

AU - Laut, Sophie S.

AU - Olivier, Scot S.

AU - Izatt, Joseph A.

AU - Werner, John S

PY - 2006

Y1 - 2006

N2 - Adaptive Optics - Optical Coherence Tomography (AO-OCT) has demonstrated a promising improvement in lateral resolution for retinal imaging compared to standard OCT. Recent developments in Fourier-domain OCT technology allow AO-OCT instruments to acquire three-dimensional (3D) retinal structures with high speed and high "volumetric" resolution (in all three dimensions). One of the most important factors (besides acquisition speed) that will determine the true potential of this technique is its ability to achieve diffraction-limited lateral resolution (∼3 μn) while operating in the ultrahigh axial resolution range (∼3 μn) offered by OCT. Theoretical studies have shown that the eye's chromatic aberrations may drastically reduce volumetric resolution. This is a critical finding because for "standard" stand alone ultrahigh OCT, increasing the spectral bandwidth of the light source improves axial resolution without compromising lateral resolution. To study the effects of spectral bandwidth on AO-OCT systems for retinal imaging two different light sources offering 6 and 3 μn axial resolution were tested. This comparison was based on both AO correcting system performance as well as the quality of corresponding OCT images.

AB - Adaptive Optics - Optical Coherence Tomography (AO-OCT) has demonstrated a promising improvement in lateral resolution for retinal imaging compared to standard OCT. Recent developments in Fourier-domain OCT technology allow AO-OCT instruments to acquire three-dimensional (3D) retinal structures with high speed and high "volumetric" resolution (in all three dimensions). One of the most important factors (besides acquisition speed) that will determine the true potential of this technique is its ability to achieve diffraction-limited lateral resolution (∼3 μn) while operating in the ultrahigh axial resolution range (∼3 μn) offered by OCT. Theoretical studies have shown that the eye's chromatic aberrations may drastically reduce volumetric resolution. This is a critical finding because for "standard" stand alone ultrahigh OCT, increasing the spectral bandwidth of the light source improves axial resolution without compromising lateral resolution. To study the effects of spectral bandwidth on AO-OCT systems for retinal imaging two different light sources offering 6 and 3 μn axial resolution were tested. This comparison was based on both AO correcting system performance as well as the quality of corresponding OCT images.

KW - Aberration compensation

KW - Adaptive optics

KW - Medical optics instrumentation

KW - Ophthalmology

KW - Optical coherence tomography

UR - http://www.scopus.com/inward/record.url?scp=33745384416&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33745384416&partnerID=8YFLogxK

U2 - 10.1117/12.647540

DO - 10.1117/12.647540

M3 - Conference contribution

AN - SCOPUS:33745384416

SN - 0819461814

SN - 9780819461810

VL - 6138

BT - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

ER -