Abstract
We have combined Fourier-domain optical coherence tomography (FD-OCT) with a closed-loop adaptive optics (AO) system using a Hartmann-Shack wavefront sensor and a bimorph deformable mirror. The adaptive optics system measures and corrects the wavefront aberration of the human eye for improved lateral resolution (∼4 μm) of retinal images, while maintaining the high axial resolution (∼6 μm) of stand alone OCT. The AO-OCT instrument enables the three-dimensional (3D) visualization of different retinal structures in vivo with high 3D resolution (4×4×6 μm). Using this system, we have demonstrated the ability to image microscopic blood vessels and the cone photoreceptor mosaic.
| Original language | English (US) |
|---|---|
| Journal | Optics Express |
| Volume | 13 |
| Issue number | 21 |
| State | Published - Oct 17 2005 |
ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics
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Zawadzki, R. J., Jones, S. M., Olivier, S. S., Zhao, M., Bower, B. A., Izatt, J. A., Choi, S., Laut, S., & Werner, J. S. (2005). Adaptive-optics optical coherence tomography for high-resolution and high-speed 3D retinal in vivo imaging. Optics Express, 13(21).