Acute Rhabdomyolysis Associated with Cocaine Intoxication

Ramkrishna Kothur, Gerald L. Posner, Anne A Knowlton, Cecelia Hard, Barry Herzlich, Edward Arsura, Murali Pagala, David Grob, David Roth, Jacques J. Bourgoignie

Research output: Contribution to journalLetter

8 Citations (Scopus)

Abstract

To the Editor: In the article entitled “Acute Rhabdomyolysis Associated with Cocaine Intoxication” (Sept. 15 issue),* Dr. Roth and his colleagues reported 11 cases of hepatic dysfunction in 13 patients with renal failure. Six of the 11 patients were hypotensive on admission. Two patients without renal failure also had hepatic dysfunction, but concomitant hypotension was not mentioned. Roth et al. consider that hypotension may be partly responsible for hepatic dysfunction. They did not report the time course of the hepatic enzyme abnormalities. In “shock liver,” the enzyme levels increase dramatically, with rapid normalization within a few days once hypotension is…

Original languageEnglish (US)
Pages (from-to)667-668
Number of pages2
JournalNew England Journal of Medicine
Volume320
Issue number10
DOIs
StatePublished - Mar 9 1989
Externally publishedYes

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Rhabdomyolysis
Cocaine
Liver
Hypotension
Renal Insufficiency
Enzymes
Shock

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Kothur, R., Posner, G. L., Knowlton, A. A., Hard, C., Herzlich, B., Arsura, E., ... Bourgoignie, J. J. (1989). Acute Rhabdomyolysis Associated with Cocaine Intoxication. New England Journal of Medicine, 320(10), 667-668. https://doi.org/10.1056/NEJM198903093201011

Acute Rhabdomyolysis Associated with Cocaine Intoxication. / Kothur, Ramkrishna; Posner, Gerald L.; Knowlton, Anne A; Hard, Cecelia; Herzlich, Barry; Arsura, Edward; Pagala, Murali; Grob, David; Roth, David; Bourgoignie, Jacques J.

In: New England Journal of Medicine, Vol. 320, No. 10, 09.03.1989, p. 667-668.

Research output: Contribution to journalLetter

Kothur, R, Posner, GL, Knowlton, AA, Hard, C, Herzlich, B, Arsura, E, Pagala, M, Grob, D, Roth, D & Bourgoignie, JJ 1989, 'Acute Rhabdomyolysis Associated with Cocaine Intoxication', New England Journal of Medicine, vol. 320, no. 10, pp. 667-668. https://doi.org/10.1056/NEJM198903093201011
Kothur, Ramkrishna ; Posner, Gerald L. ; Knowlton, Anne A ; Hard, Cecelia ; Herzlich, Barry ; Arsura, Edward ; Pagala, Murali ; Grob, David ; Roth, David ; Bourgoignie, Jacques J. / Acute Rhabdomyolysis Associated with Cocaine Intoxication. In: New England Journal of Medicine. 1989 ; Vol. 320, No. 10. pp. 667-668.
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