Acute Retinal Necrosis Presenting in Developmentally-delayed Patients with Neonatal Encephalitis: A Case Series and Literature Review

Kingsley Okafor, Jonathan Liu, Sumeer Thinda, Ivan Schwab, Lawrence S Morse, Susanna Soon Chun Park, Ala Moshiri

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We report three cases of patients with developmental-delay from neonatal herpetic encephalitis and/or meningitis who presented years later with acute retinal necrosis due to herpes simplex virus. The diagnosis was delayed in all cases due to the patients’ inability to verbalize their ocular complaints and cooperate with eye examinations. This case series documents the clinical course, pathophysiologic mechanism, and treatment of acute retinal necrosis in this patient population. Clinicians should understand the importance of prudent consideration of acute retinal necrosis in patients with a history of neonatal herpetic encephalitis and/or meningitis presenting with a red eye.

Original languageEnglish (US)
Pages (from-to)1-6
Number of pages6
JournalOcular Immunology and Inflammation
DOIs
StateAccepted/In press - May 20 2016

Fingerprint

Acute Retinal Necrosis Syndrome
Encephalitis
Herpes Simplex Encephalitis
Meningitis
Delayed Diagnosis
Simplexvirus
Population

Keywords

  • ARN
  • encephalitis
  • herpes
  • retinitis
  • uveitis

ASJC Scopus subject areas

  • Ophthalmology
  • Immunology and Allergy

Cite this

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abstract = "We report three cases of patients with developmental-delay from neonatal herpetic encephalitis and/or meningitis who presented years later with acute retinal necrosis due to herpes simplex virus. The diagnosis was delayed in all cases due to the patients’ inability to verbalize their ocular complaints and cooperate with eye examinations. This case series documents the clinical course, pathophysiologic mechanism, and treatment of acute retinal necrosis in this patient population. Clinicians should understand the importance of prudent consideration of acute retinal necrosis in patients with a history of neonatal herpetic encephalitis and/or meningitis presenting with a red eye.",
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AU - Thinda, Sumeer

AU - Schwab, Ivan

AU - Morse, Lawrence S

AU - Park, Susanna Soon Chun

AU - Moshiri, Ala

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AB - We report three cases of patients with developmental-delay from neonatal herpetic encephalitis and/or meningitis who presented years later with acute retinal necrosis due to herpes simplex virus. The diagnosis was delayed in all cases due to the patients’ inability to verbalize their ocular complaints and cooperate with eye examinations. This case series documents the clinical course, pathophysiologic mechanism, and treatment of acute retinal necrosis in this patient population. Clinicians should understand the importance of prudent consideration of acute retinal necrosis in patients with a history of neonatal herpetic encephalitis and/or meningitis presenting with a red eye.

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KW - uveitis

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