Abstract
Although there are reports of myocardial infarction (MI) in patients with sickle cell diseases, an antemortem diagnosis of acute MI in a patient with compound heterozygous hemoglobin SC disease has not been reported. Herein, we present a patient with hemoglobin SC who suffered an acute MI. She had typical chest pain for myocardial ischemia, associated with ST elevations on the electrocardiogram (EKG) and elevations of cardiac injury markers diagnostic of infarction. The patient was treated with conventional therapies for acute coronary syndrome and also emergent red blood cell exchange. Interestingly, coronary angiography was completely normal in this patient. Potential mechanisms and management for acute MI in patients with sickle cell disease are discussed.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 622-624 |
| Number of pages | 3 |
| Journal | Annals of Hematology |
| Volume | 83 |
| Issue number | 10 |
| DOIs | |
| State | Published - Oct 2004 |
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Keywords
- Diagnosis
- Hemoglobin SC disease
- Myocardial infarction
- Treatment
ASJC Scopus subject areas
- Hematology
Cite this
Acute myocardial infarction in hemoglobin SC disease. / Wang, Henry; Laslett, Lawrence J.; Richman, Carol M; Wun, Theodore.
In: Annals of Hematology, Vol. 83, No. 10, 10.2004, p. 622-624.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Acute myocardial infarction in hemoglobin SC disease
AU - Wang, Henry
AU - Laslett, Lawrence J.
AU - Richman, Carol M
AU - Wun, Theodore
PY - 2004/10
Y1 - 2004/10
N2 - Although there are reports of myocardial infarction (MI) in patients with sickle cell diseases, an antemortem diagnosis of acute MI in a patient with compound heterozygous hemoglobin SC disease has not been reported. Herein, we present a patient with hemoglobin SC who suffered an acute MI. She had typical chest pain for myocardial ischemia, associated with ST elevations on the electrocardiogram (EKG) and elevations of cardiac injury markers diagnostic of infarction. The patient was treated with conventional therapies for acute coronary syndrome and also emergent red blood cell exchange. Interestingly, coronary angiography was completely normal in this patient. Potential mechanisms and management for acute MI in patients with sickle cell disease are discussed.
AB - Although there are reports of myocardial infarction (MI) in patients with sickle cell diseases, an antemortem diagnosis of acute MI in a patient with compound heterozygous hemoglobin SC disease has not been reported. Herein, we present a patient with hemoglobin SC who suffered an acute MI. She had typical chest pain for myocardial ischemia, associated with ST elevations on the electrocardiogram (EKG) and elevations of cardiac injury markers diagnostic of infarction. The patient was treated with conventional therapies for acute coronary syndrome and also emergent red blood cell exchange. Interestingly, coronary angiography was completely normal in this patient. Potential mechanisms and management for acute MI in patients with sickle cell disease are discussed.
KW - Diagnosis
KW - Hemoglobin SC disease
KW - Myocardial infarction
KW - Treatment
UR - http://www.scopus.com/inward/record.url?scp=4844225934&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=4844225934&partnerID=8YFLogxK
U2 - 10.1007/s00277-004-0907-2
DO - 10.1007/s00277-004-0907-2
M3 - Article
C2 - 15300406
AN - SCOPUS:4844225934
VL - 83
SP - 622
EP - 624
JO - Annals of Hematology
JF - Annals of Hematology
SN - 0939-5555
IS - 10
ER -