Acute myocardial infarction in hemoglobin SC disease

Henry Wang, Lawrence J. Laslett, Carol M Richman, Theodore Wun

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Although there are reports of myocardial infarction (MI) in patients with sickle cell diseases, an antemortem diagnosis of acute MI in a patient with compound heterozygous hemoglobin SC disease has not been reported. Herein, we present a patient with hemoglobin SC who suffered an acute MI. She had typical chest pain for myocardial ischemia, associated with ST elevations on the electrocardiogram (EKG) and elevations of cardiac injury markers diagnostic of infarction. The patient was treated with conventional therapies for acute coronary syndrome and also emergent red blood cell exchange. Interestingly, coronary angiography was completely normal in this patient. Potential mechanisms and management for acute MI in patients with sickle cell disease are discussed.

Original languageEnglish (US)
Pages (from-to)622-624
Number of pages3
JournalAnnals of Hematology
Volume83
Issue number10
DOIs
StatePublished - Oct 2004

Fingerprint

Hemoglobin SC Disease
Myocardial Infarction
Sickle Cell Anemia
Electrocardiography
Acute Coronary Syndrome
Coronary Angiography
Chest Pain
Infarction
Myocardial Ischemia
Hemoglobins
Erythrocytes
Wounds and Injuries

Keywords

  • Diagnosis
  • Hemoglobin SC disease
  • Myocardial infarction
  • Treatment

ASJC Scopus subject areas

  • Hematology

Cite this

Acute myocardial infarction in hemoglobin SC disease. / Wang, Henry; Laslett, Lawrence J.; Richman, Carol M; Wun, Theodore.

In: Annals of Hematology, Vol. 83, No. 10, 10.2004, p. 622-624.

Research output: Contribution to journalArticle

Wang, Henry ; Laslett, Lawrence J. ; Richman, Carol M ; Wun, Theodore. / Acute myocardial infarction in hemoglobin SC disease. In: Annals of Hematology. 2004 ; Vol. 83, No. 10. pp. 622-624.
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