Acute myocardial infarction in hemoglobin SC disease

Henry Wang, Lawrence J. Laslett, Carol M Richman, Theodore Wun

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Although there are reports of myocardial infarction (MI) in patients with sickle cell diseases, an antemortem diagnosis of acute MI in a patient with compound heterozygous hemoglobin SC disease has not been reported. Herein, we present a patient with hemoglobin SC who suffered an acute MI. She had typical chest pain for myocardial ischemia, associated with ST elevations on the electrocardiogram (EKG) and elevations of cardiac injury markers diagnostic of infarction. The patient was treated with conventional therapies for acute coronary syndrome and also emergent red blood cell exchange. Interestingly, coronary angiography was completely normal in this patient. Potential mechanisms and management for acute MI in patients with sickle cell disease are discussed.

Original languageEnglish (US)
Pages (from-to)622-624
Number of pages3
JournalAnnals of Hematology
Issue number10
StatePublished - Oct 2004


  • Diagnosis
  • Hemoglobin SC disease
  • Myocardial infarction
  • Treatment

ASJC Scopus subject areas

  • Hematology


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