Acute myocardial infarction in hemoglobin SC disease

Henry Wang; Lawrence J. Laslett; Carol M Richman; Theodore Wun

doi:10.1007/s00277-004-0907-2

Acute myocardial infarction in hemoglobin SC disease

Henry Wang, Lawrence J. Laslett, Carol M Richman, Theodore Wun

Hematology and Oncology

Research output: Contribution to journal › Article

11 Scopus citations

Abstract

Although there are reports of myocardial infarction (MI) in patients with sickle cell diseases, an antemortem diagnosis of acute MI in a patient with compound heterozygous hemoglobin SC disease has not been reported. Herein, we present a patient with hemoglobin SC who suffered an acute MI. She had typical chest pain for myocardial ischemia, associated with ST elevations on the electrocardiogram (EKG) and elevations of cardiac injury markers diagnostic of infarction. The patient was treated with conventional therapies for acute coronary syndrome and also emergent red blood cell exchange. Interestingly, coronary angiography was completely normal in this patient. Potential mechanisms and management for acute MI in patients with sickle cell disease are discussed.

Original language	English (US)
Pages (from-to)	622-624
Number of pages	3
Journal	Annals of Hematology
Volume	83
Issue number	10
DOIs	https://doi.org/10.1007/s00277-004-0907-2
State	Published - Oct 2004

Fingerprint

Keywords

Diagnosis
Hemoglobin SC disease
Myocardial infarction
Treatment

ASJC Scopus subject areas

Hematology

Cite this

Wang, H., Laslett, L. J., Richman, C. M., & Wun, T. (2004). Acute myocardial infarction in hemoglobin SC disease. Annals of Hematology, 83(10), 622-624. https://doi.org/10.1007/s00277-004-0907-2

@article{ad27ce216e454d9ab45af5b7088ab3f3,

title = "Acute myocardial infarction in hemoglobin SC disease",

abstract = "Although there are reports of myocardial infarction (MI) in patients with sickle cell diseases, an antemortem diagnosis of acute MI in a patient with compound heterozygous hemoglobin SC disease has not been reported. Herein, we present a patient with hemoglobin SC who suffered an acute MI. She had typical chest pain for myocardial ischemia, associated with ST elevations on the electrocardiogram (EKG) and elevations of cardiac injury markers diagnostic of infarction. The patient was treated with conventional therapies for acute coronary syndrome and also emergent red blood cell exchange. Interestingly, coronary angiography was completely normal in this patient. Potential mechanisms and management for acute MI in patients with sickle cell disease are discussed.",

keywords = "Diagnosis, Hemoglobin SC disease, Myocardial infarction, Treatment",

author = "Henry Wang and Laslett, {Lawrence J.} and Richman, {Carol M} and Theodore Wun",

year = "2004",

month = oct

doi = "10.1007/s00277-004-0907-2",

language = "English (US)",

volume = "83",

pages = "622--624",

journal = "Annals of Hematology",

issn = "0939-5555",

publisher = "Springer Verlag",

number = "10",

}

TY - JOUR

T1 - Acute myocardial infarction in hemoglobin SC disease

AU - Wang, Henry

AU - Laslett, Lawrence J.

AU - Richman, Carol M

AU - Wun, Theodore

PY - 2004/10

Y1 - 2004/10

N2 - Although there are reports of myocardial infarction (MI) in patients with sickle cell diseases, an antemortem diagnosis of acute MI in a patient with compound heterozygous hemoglobin SC disease has not been reported. Herein, we present a patient with hemoglobin SC who suffered an acute MI. She had typical chest pain for myocardial ischemia, associated with ST elevations on the electrocardiogram (EKG) and elevations of cardiac injury markers diagnostic of infarction. The patient was treated with conventional therapies for acute coronary syndrome and also emergent red blood cell exchange. Interestingly, coronary angiography was completely normal in this patient. Potential mechanisms and management for acute MI in patients with sickle cell disease are discussed.

AB - Although there are reports of myocardial infarction (MI) in patients with sickle cell diseases, an antemortem diagnosis of acute MI in a patient with compound heterozygous hemoglobin SC disease has not been reported. Herein, we present a patient with hemoglobin SC who suffered an acute MI. She had typical chest pain for myocardial ischemia, associated with ST elevations on the electrocardiogram (EKG) and elevations of cardiac injury markers diagnostic of infarction. The patient was treated with conventional therapies for acute coronary syndrome and also emergent red blood cell exchange. Interestingly, coronary angiography was completely normal in this patient. Potential mechanisms and management for acute MI in patients with sickle cell disease are discussed.

KW - Diagnosis

KW - Hemoglobin SC disease

KW - Myocardial infarction

KW - Treatment

UR - http://www.scopus.com/inward/record.url?scp=4844225934&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=4844225934&partnerID=8YFLogxK

U2 - 10.1007/s00277-004-0907-2

DO - 10.1007/s00277-004-0907-2

M3 - Article

C2 - 15300406

AN - SCOPUS:4844225934

VL - 83

SP - 622

EP - 624

JO - Annals of Hematology

JF - Annals of Hematology

SN - 0939-5555

IS - 10

ER -

Access to Document

10.1007/s00277-004-0907-2