Acute myelomonocytic leukemia in a horse.

S. J. Spier, B. R. Madewell, J. G. Zinkl, A. M. Ryan

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


A 7-year-old Quarter Horse stallion with a myeloproliferative disorder was examined because of colic, and an enterolith was removed surgically. The horse experienced secondary complications after abdominal surgery, and leukopenia and thrombocytopenia were detected. Five months later, the horse was examined for recurrent peripheral edema and for repair of an abdominal incisional hernia. Acute myelomonocytic leukemia was diagnosed, and treatment with low-dose (noncytocidal) cytosine arabinoside was unsuccessful. Necropsy revealed neoplastic infiltrate in the spleen, liver, lung, adrenal gland, testes, and eye. The persistent hematologic abnormalities before the onset of overt leukemia may represent hematopoietic dysplasia or preleukemia.

Original languageEnglish (US)
Pages (from-to)861-863
Number of pages3
JournalJournal of the American Veterinary Medical Association
Issue number8
StatePublished - Apr 15 1986

ASJC Scopus subject areas

  • veterinary(all)


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