TY - JOUR
T1 - Acute myelomonocytic leukaemia with short-term spontaneous remission in a cat
AU - Mylonakis, M. E.
AU - Petanides, T. A.
AU - Valli, V. E.
AU - Vernau, William
AU - Koytinas, A. F.
AU - Michael, R. S.
PY - 2008/6
Y1 - 2008/6
N2 - A 2-year-old, spayed female domestic shorthair cat was referred with a history of anorexia and depression of 1 week duration. On physical examination, the cat was lethargic and febrile, with splenomegaly, anisocoria and ulcerative stomatitis. A complete blood count (CBC) and a biochemistry profile showed leukocytosis, numerous blast cells in the peripheral blood, thrombocytopenia, hyperglobulinaemia and a positive test for feline leukaemia virus antigen. A diagnosis of acute myelomonocytic leukaemia was made on the basis of the results of bone marrow cytology, histopathology, and immunochemistry (CD3, CD79a, lysozyme, and myeloperoxidase) tests. Following an unexpected 1-month period of clinical and clinicopathological remission without chemotherapy, the cat relapsed and died 1 week later.
AB - A 2-year-old, spayed female domestic shorthair cat was referred with a history of anorexia and depression of 1 week duration. On physical examination, the cat was lethargic and febrile, with splenomegaly, anisocoria and ulcerative stomatitis. A complete blood count (CBC) and a biochemistry profile showed leukocytosis, numerous blast cells in the peripheral blood, thrombocytopenia, hyperglobulinaemia and a positive test for feline leukaemia virus antigen. A diagnosis of acute myelomonocytic leukaemia was made on the basis of the results of bone marrow cytology, histopathology, and immunochemistry (CD3, CD79a, lysozyme, and myeloperoxidase) tests. Following an unexpected 1-month period of clinical and clinicopathological remission without chemotherapy, the cat relapsed and died 1 week later.
KW - Acute myelomonocytic leukaemia
KW - Cat
KW - Myeloid neoplasms
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U2 - 10.1111/j.1751-0813.2008.00304.x
DO - 10.1111/j.1751-0813.2008.00304.x
M3 - Article
C2 - 18498558
AN - SCOPUS:44349126643
VL - 86
SP - 224
EP - 228
JO - Australian Veterinary Journal
JF - Australian Veterinary Journal
SN - 0005-0423
IS - 6
ER -