Acute myeloid leukemia risk by industry and occupation

Rebecca J. Tsai, Sara E. Luckhaupt, Pam Schumacher, Rosemary D Cress, Dennis M. Deapen, Geoffrey M. Calvert

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

Acute myeloid leukemia (AML) is the most common type of leukemia found in adults. Identifying jobs that pose a risk for AML may be useful for identifying new risk factors. A matched case-control analysis was conducted using California Cancer Registry data from 1988 to 2007. This study included 8999 cases of AML and 24 822 controls. Industries with a statistically significant increased AML risk were construction (matched odds ratio [mOR] = 1.13); crop production (mOR = 1.41); support activities for agriculture and forestry (mOR = 2.05); and animal slaughtering and processing (mOR = 2.09). Among occupations with a statistically significant increased AML risk were miscellaneous agricultural workers (mOR = 1.76); fishers and related fishing workers (mOR = 2.02); nursing, psychiatric and home health aides (mOR = 1.65); and janitors and building cleaners (mOR = 1.54). Further investigation is needed to confirm study findings and to identify specific exposures responsible for the increased risks.

Original languageEnglish (US)
Pages (from-to)2584-2591
Number of pages8
JournalLeukemia and Lymphoma
Volume55
Issue number11
DOIs
StatePublished - Nov 1 2014

Keywords

  • Acute myeloid leukemia
  • Industry
  • Occupation
  • Risk factors

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

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  • Cite this

    Tsai, R. J., Luckhaupt, S. E., Schumacher, P., Cress, R. D., Deapen, D. M., & Calvert, G. M. (2014). Acute myeloid leukemia risk by industry and occupation. Leukemia and Lymphoma, 55(11), 2584-2591. https://doi.org/10.3109/10428194.2014.894189