Abstract
Aspirin, ketoprofen, ibuprofen, and naproxen all produced acute gastric erosions in rats. Aspirin produced significantly more erosions than ketoprofen, ibuprofen, or naproxen. There was no significant difference between the effects of ketoprofen, ibuprofen, and naproxen. Aspirin and naproxen produced a synergistic effect at higher dosage. Metiamide and cimetidine were effective in preventing this type of experimental acute erosive gastritis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 562-564 |
| Number of pages | 3 |
| Journal | Southern Medical Journal |
| Volume | 70 |
| Issue number | 5 |
| State | Published - 1977 |
| Externally published | Yes |
ASJC Scopus subject areas
- Medicine(all)
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Mann, N. S., & Sachdev, A. J. (1977). Acute erosive gastritis induced by aspirin, ketoprofen, ibuprofen, and naproxen: Its prevention by metiamide and cimetidine. Southern Medical Journal, 70(5), 562-564.