Acute erosive gastritis induced by aspirin, ketoprofen, ibuprofen, and naproxen: Its prevention by metiamide and cimetidine

Nirmal S Mann; A. J. Sachdev

Acute erosive gastritis induced by aspirin, ketoprofen, ibuprofen, and naproxen: Its prevention by metiamide and cimetidine

Research output: Contribution to journal › Article › peer-review

Abstract

Aspirin, ketoprofen, ibuprofen, and naproxen all produced acute gastric erosions in rats. Aspirin produced significantly more erosions than ketoprofen, ibuprofen, or naproxen. There was no significant difference between the effects of ketoprofen, ibuprofen, and naproxen. Aspirin and naproxen produced a synergistic effect at higher dosage. Metiamide and cimetidine were effective in preventing this type of experimental acute erosive gastritis.

Original language	English (US)
Pages (from-to)	562-564
Number of pages	3
Journal	Southern Medical Journal
Volume	70
Issue number	5
State	Published - 1977
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

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abstract = "Aspirin, ketoprofen, ibuprofen, and naproxen all produced acute gastric erosions in rats. Aspirin produced significantly more erosions than ketoprofen, ibuprofen, or naproxen. There was no significant difference between the effects of ketoprofen, ibuprofen, and naproxen. Aspirin and naproxen produced a synergistic effect at higher dosage. Metiamide and cimetidine were effective in preventing this type of experimental acute erosive gastritis.",

author = "Mann, {Nirmal S} and Sachdev, {A. J.}",

year = "1977",

language = "English (US)",

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AU - Sachdev, A. J.

PY - 1977

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AB - Aspirin, ketoprofen, ibuprofen, and naproxen all produced acute gastric erosions in rats. Aspirin produced significantly more erosions than ketoprofen, ibuprofen, or naproxen. There was no significant difference between the effects of ketoprofen, ibuprofen, and naproxen. Aspirin and naproxen produced a synergistic effect at higher dosage. Metiamide and cimetidine were effective in preventing this type of experimental acute erosive gastritis.

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Acute erosive gastritis induced by aspirin, ketoprofen, ibuprofen, and naproxen: Its prevention by metiamide and cimetidine

Abstract

ASJC Scopus subject areas

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