Activation of sexual reflexes of male rats by dihydrotestosterone but not estrogen

Research output: Contribution to journalArticle

77 Citations (Scopus)

Abstract

Previous studies have shown that withdrawal and administration of testosterone propionate (TP) has a quantitative influence on sexual reflexes which parallels changes in copulatory activity following castration and administration of TP. The present study involving castrated spinal male rats explored further this parallel, focusing on the effects on sexual reflexes of the administration of dihydrotestosterone propionate (DHTP) and estradiol benzoate (EB), both of which can activate sexual behavior in spinally intact castrated male rats, but only if given in very large doses for a prolonged period of time. A parallel effect on reflexes and behavior was not found inasmuch as DHTP activated sexual reflexes at a dose (200 μg daily) considerably below that needed to activate behavior, and EB did not appreciably activate reflexes, even after prolonged treatment at levels (100-200 μg) higher than necessary to activate behavior. The results, with EB in particular, point out that the display of intromissive and ejaculatory patterns in rats may not involve spinal neural mechanisms that are customarily associated with these behavioral patterns.

Original languageEnglish (US)
Pages (from-to)107-109
Number of pages3
JournalPhysiology and Behavior
Volume23
Issue number1
DOIs
StatePublished - Jan 1 1979
Externally publishedYes

Fingerprint

Dihydrotestosterone
Reflex
Estrogens
Testosterone Propionate
Castration
Sexual Behavior
estradiol 3-benzoate
dihydrotestosterone propionate

Keywords

  • Hormones
  • Sexual behavior
  • Sexual reflexes
  • Spinal cord

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Behavioral Neuroscience

Cite this

Activation of sexual reflexes of male rats by dihydrotestosterone but not estrogen. / Hart, Benjamin.

In: Physiology and Behavior, Vol. 23, No. 1, 01.01.1979, p. 107-109.

Research output: Contribution to journalArticle

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