Abstract
Massive transfusion protocol (MTP) is used to resuscitate patients in hemorrhagic shock. Our goal was to review MTP use in the elderly. All trauma patients who required activation of MTP at an urban Level I trauma center from January 1, 2011 to December 31, 2013 were reviewed retrospectively. Elderly was defined as age . 60 years. Sixtysix patients had MTP activated: 52 nonelderly (NE) and 14 elderly (E). There were no statistically significant differences between the two cohorts for gender, injury severity score, head abbreviated injury scale, emergency department Glasgow Coma Scale, initial hematocrit, intensive care unit length of stay, or hospital length of stay. Mean age for NE was 35 years and 73 years for E (P < 0.01). Less than half (43%) of E patients with activation of MTP received 10 or more units of blood products compared with 69 per cent of the NE (P = 0.07). Mortality rates were similar in the NE and the E (53%vs 50%, P = 0.80). After multivariate analysis with Glasgow Coma Scale, injury severity score, and blunt versus penetrating trauma, elderly age was not a predictor of mortality after MTP (P = 0.35). When MTP is activated, survival to discharge in elderly trauma patients is comparable to younger patients.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 945-949 |
| Number of pages | 5 |
| Journal | American Surgeon |
| Volume | 81 |
| Issue number | 10 |
| State | Published - Jan 1 2015 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Surgery
- Medicine(all)
Cite this
Activation of massive transfusion for elderly trauma patients. / Murry, Jason S.; Zaw, Andrea A.; Hoang, David M.; Mehrzadi, Devorah; Tran, Danielle; Nuno, Miriam A; Bloom, Matthew; Melo, Nicolas; Margulies, Daniel R.; Ley, Eric J.
In: American Surgeon, Vol. 81, No. 10, 01.01.2015, p. 945-949.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Activation of massive transfusion for elderly trauma patients
AU - Murry, Jason S.
AU - Zaw, Andrea A.
AU - Hoang, David M.
AU - Mehrzadi, Devorah
AU - Tran, Danielle
AU - Nuno, Miriam A
AU - Bloom, Matthew
AU - Melo, Nicolas
AU - Margulies, Daniel R.
AU - Ley, Eric J.
PY - 2015/1/1
Y1 - 2015/1/1
N2 - Massive transfusion protocol (MTP) is used to resuscitate patients in hemorrhagic shock. Our goal was to review MTP use in the elderly. All trauma patients who required activation of MTP at an urban Level I trauma center from January 1, 2011 to December 31, 2013 were reviewed retrospectively. Elderly was defined as age . 60 years. Sixtysix patients had MTP activated: 52 nonelderly (NE) and 14 elderly (E). There were no statistically significant differences between the two cohorts for gender, injury severity score, head abbreviated injury scale, emergency department Glasgow Coma Scale, initial hematocrit, intensive care unit length of stay, or hospital length of stay. Mean age for NE was 35 years and 73 years for E (P < 0.01). Less than half (43%) of E patients with activation of MTP received 10 or more units of blood products compared with 69 per cent of the NE (P = 0.07). Mortality rates were similar in the NE and the E (53%vs 50%, P = 0.80). After multivariate analysis with Glasgow Coma Scale, injury severity score, and blunt versus penetrating trauma, elderly age was not a predictor of mortality after MTP (P = 0.35). When MTP is activated, survival to discharge in elderly trauma patients is comparable to younger patients.
AB - Massive transfusion protocol (MTP) is used to resuscitate patients in hemorrhagic shock. Our goal was to review MTP use in the elderly. All trauma patients who required activation of MTP at an urban Level I trauma center from January 1, 2011 to December 31, 2013 were reviewed retrospectively. Elderly was defined as age . 60 years. Sixtysix patients had MTP activated: 52 nonelderly (NE) and 14 elderly (E). There were no statistically significant differences between the two cohorts for gender, injury severity score, head abbreviated injury scale, emergency department Glasgow Coma Scale, initial hematocrit, intensive care unit length of stay, or hospital length of stay. Mean age for NE was 35 years and 73 years for E (P < 0.01). Less than half (43%) of E patients with activation of MTP received 10 or more units of blood products compared with 69 per cent of the NE (P = 0.07). Mortality rates were similar in the NE and the E (53%vs 50%, P = 0.80). After multivariate analysis with Glasgow Coma Scale, injury severity score, and blunt versus penetrating trauma, elderly age was not a predictor of mortality after MTP (P = 0.35). When MTP is activated, survival to discharge in elderly trauma patients is comparable to younger patients.
UR - http://www.scopus.com/inward/record.url?scp=84944096740&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84944096740&partnerID=8YFLogxK
M3 - Article
C2 - 26463286
AN - SCOPUS:84944096740
VL - 81
SP - 945
EP - 949
JO - American Surgeon
JF - American Surgeon
SN - 0003-1348
IS - 10
ER -