Activated Charcoal Reduces Lactulose-Induced Breath Hydrogen in Patients with Excessive Gas and in Controls

Nirmal S Mann, Eddie Cheung

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Objective: To evaluate the effect of activated charcoal on lactulose-induced breath hydrogen flatus passage and abdominal bloating in healthy controls and patients with complaints of excessive gas. Patients and Methods: Five male healthy controls and six male patients with complaints of excessive gas were enrolled. Breath H2, flatus passage and abdominal bloating was noted after oral lactulose over an 8 hour period in both controls and patients. Effect of activated charcoal on all these parameters was evaluated. Results: Patients produced more breath H2, more flatus and more bloating after oral lactulose compared to controls. Activated charcoal improved all these parameters in both patients and controls. Conclusion: Activated charcoal is effective in reducing breath H2 flatus passage and abdominal bloating in response to oral lactulose.

Original languageEnglish (US)
Pages (from-to)295-297
Number of pages3
JournalInternational Medical Journal
Volume10
Issue number4
StatePublished - Dec 2003

Fingerprint

Lactulose
Charcoal
Flatulence
Hydrogen
Gases

Keywords

  • Activated charcoal
  • Breath H
  • Flatus
  • Lactulose

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Activated Charcoal Reduces Lactulose-Induced Breath Hydrogen in Patients with Excessive Gas and in Controls. / Mann, Nirmal S; Cheung, Eddie.

In: International Medical Journal, Vol. 10, No. 4, 12.2003, p. 295-297.

Research output: Contribution to journalArticle

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AB - Objective: To evaluate the effect of activated charcoal on lactulose-induced breath hydrogen flatus passage and abdominal bloating in healthy controls and patients with complaints of excessive gas. Patients and Methods: Five male healthy controls and six male patients with complaints of excessive gas were enrolled. Breath H2, flatus passage and abdominal bloating was noted after oral lactulose over an 8 hour period in both controls and patients. Effect of activated charcoal on all these parameters was evaluated. Results: Patients produced more breath H2, more flatus and more bloating after oral lactulose compared to controls. Activated charcoal improved all these parameters in both patients and controls. Conclusion: Activated charcoal is effective in reducing breath H2 flatus passage and abdominal bloating in response to oral lactulose.

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