Action of microbubbles when insonified: experimental evidence

P. Dayton, A. Goode, K. Morgan, S. Klibanov, G. Brandenburger, K. Ferrara

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Scopus citations


Primary and secondary Bjerknes forces result from pressure gradients in the incident and scattered ultrasonic fields. These forces and their dependence on experimental parameters are described. Both primary and secondary Bjerknes forces are shown to have a significant effect on the flow of microbubbles through a small vessel during insonation. The primary Bjerknes force produces displacement of microspheres across a 100 micron vessel radius for a small transmitted acoustic power. The secondary Bjerknes force produces a reversible attraction and aggregation of microspheres with a significant attraction over a distance of approximately 100 microns. The magnitude of the secondary Bjerknes force is proportional to the inverse of the squared separation distance, and thus two aggregates accelerate as they approach one another.

Original languageEnglish (US)
Title of host publicationProceedings of the IEEE Ultrasonics Symposium
EditorsM. Levy, S.C. Schneider, B.R. McAvoy
Number of pages4
StatePublished - 1996
Externally publishedYes
EventProceedings of the 1996 IEEE Ultrasonics Symposium. Part 2 (of 2) - San Antonio, TX, USA
Duration: Nov 3 1996Nov 6 1996


OtherProceedings of the 1996 IEEE Ultrasonics Symposium. Part 2 (of 2)
CitySan Antonio, TX, USA

ASJC Scopus subject areas

  • Engineering(all)


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