Abstract
Acrodermatitis enteropathica is a rare autosomal recessive disorder of zinc deficiency. The genetic defect has been mapped to 8q24 and the defective gene identified as SLC39A4, which encodes the zinc transporter Zip4. The diagnosis is made by way of clinical presentation together with histopathology and laboratory tests. Here we provide an overview of zinc metabolism and a description of inherited and acquired zinc deficiency.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 116-124 |
| Number of pages | 9 |
| Journal | Journal of the American Academy of Dermatology |
| Volume | 56 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 2007 |
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ASJC Scopus subject areas
- Dermatology
Cite this
Acrodermatitis enteropathica and an overview of zinc metabolism. / Maverakis, Emanual Michael; Fung, Maxwell A; Lynch, Peter J.; Draznin, Michelle; Michael, Daniel J.; Ruben, Beth; Fazel, Nasim.
In: Journal of the American Academy of Dermatology, Vol. 56, No. 1, 01.2007, p. 116-124.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Acrodermatitis enteropathica and an overview of zinc metabolism
AU - Maverakis, Emanual Michael
AU - Fung, Maxwell A
AU - Lynch, Peter J.
AU - Draznin, Michelle
AU - Michael, Daniel J.
AU - Ruben, Beth
AU - Fazel, Nasim
PY - 2007/1
Y1 - 2007/1
N2 - Acrodermatitis enteropathica is a rare autosomal recessive disorder of zinc deficiency. The genetic defect has been mapped to 8q24 and the defective gene identified as SLC39A4, which encodes the zinc transporter Zip4. The diagnosis is made by way of clinical presentation together with histopathology and laboratory tests. Here we provide an overview of zinc metabolism and a description of inherited and acquired zinc deficiency.
AB - Acrodermatitis enteropathica is a rare autosomal recessive disorder of zinc deficiency. The genetic defect has been mapped to 8q24 and the defective gene identified as SLC39A4, which encodes the zinc transporter Zip4. The diagnosis is made by way of clinical presentation together with histopathology and laboratory tests. Here we provide an overview of zinc metabolism and a description of inherited and acquired zinc deficiency.
UR - http://www.scopus.com/inward/record.url?scp=33845809137&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33845809137&partnerID=8YFLogxK
U2 - 10.1016/j.jaad.2006.08.015
DO - 10.1016/j.jaad.2006.08.015
M3 - Article
C2 - 17190629
AN - SCOPUS:33845809137
VL - 56
SP - 116
EP - 124
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
SN - 0190-9622
IS - 1
ER -