Acrodermatitis chronica atrophicans in the United States

Clinical and histopathologic features of six cases

D. J. DiCaudo, W. P D Su, W. F. Marshall, S. E. Malawista, Stephen W Barthold, D. H. Persing

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Acrodermatitis chronica atrophicans is a chronic cutaneous disease caused by the Lyme disease spirochete Borrelia burgdorferi. Acrodermatitis chronica atrophicans is endemic in some regions of Europe but is only rarely seen in the United States. This report describes the clinical and histopathologic findings in six cases of acrodermatitis chronica atrophicans seen at the Mayo Clinic between 1912 and 1961. Histologic differences between early and late phases of the disease were observed, and multisystemic symptoms consistent with chronic Lyme disease were documented in a subset of the patients. All five patients from whom biographical data were available were European immigrants. Our data suggest that some of the first patients with Lyme disease in the United States came to the Mayo Clinic earlier in this century.

Original languageEnglish (US)
Pages (from-to)81-84
Number of pages4
JournalCutis
Volume54
Issue number2
StatePublished - 1994
Externally publishedYes

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Acrodermatitis
Borrelia burgdorferi
Lyme Disease
Chronic Disease
Skin Diseases

ASJC Scopus subject areas

  • Dermatology
  • Immunology and Allergy

Cite this

DiCaudo, D. J., Su, W. P. D., Marshall, W. F., Malawista, S. E., Barthold, S. W., & Persing, D. H. (1994). Acrodermatitis chronica atrophicans in the United States: Clinical and histopathologic features of six cases. Cutis, 54(2), 81-84.

Acrodermatitis chronica atrophicans in the United States : Clinical and histopathologic features of six cases. / DiCaudo, D. J.; Su, W. P D; Marshall, W. F.; Malawista, S. E.; Barthold, Stephen W; Persing, D. H.

In: Cutis, Vol. 54, No. 2, 1994, p. 81-84.

Research output: Contribution to journalArticle

DiCaudo, DJ, Su, WPD, Marshall, WF, Malawista, SE, Barthold, SW & Persing, DH 1994, 'Acrodermatitis chronica atrophicans in the United States: Clinical and histopathologic features of six cases', Cutis, vol. 54, no. 2, pp. 81-84.
DiCaudo, D. J. ; Su, W. P D ; Marshall, W. F. ; Malawista, S. E. ; Barthold, Stephen W ; Persing, D. H. / Acrodermatitis chronica atrophicans in the United States : Clinical and histopathologic features of six cases. In: Cutis. 1994 ; Vol. 54, No. 2. pp. 81-84.
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