TY - JOUR
T1 - ACKR2
T2 - Nature's Decoy Receptor Lures Unsuspecting Chemokines in Psoriasis
AU - Mabuchi, Tomotaka
AU - Hwang, Samuel T
PY - 2017/1/1
Y1 - 2017/1/1
N2 - While we know much about the processes mediated by the Th17 inflammatory pathway that is crucial in psoriasis, we actually know little about the processes by which most psoriatic patients maintain what grossly looks like non-inflamed, normal skin in the face of massive inflammatory changes in nearby affected skin. Other molecular regulators that defend the skin from global inflammation are likely to be involved, including molecules such as ACKR2, an atypical chemokine receptor whose role in psoriasiform dermatitis is explored by Shams et al.
AB - While we know much about the processes mediated by the Th17 inflammatory pathway that is crucial in psoriasis, we actually know little about the processes by which most psoriatic patients maintain what grossly looks like non-inflamed, normal skin in the face of massive inflammatory changes in nearby affected skin. Other molecular regulators that defend the skin from global inflammation are likely to be involved, including molecules such as ACKR2, an atypical chemokine receptor whose role in psoriasiform dermatitis is explored by Shams et al.
UR - http://www.scopus.com/inward/record.url?scp=85006746714&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85006746714&partnerID=8YFLogxK
U2 - 10.1016/j.jid.2016.09.035
DO - 10.1016/j.jid.2016.09.035
M3 - Comment/debate
C2 - 28010760
AN - SCOPUS:85006746714
VL - 137
SP - 7
EP - 11
JO - Journal of Investigative Dermatology
JF - Journal of Investigative Dermatology
SN - 0022-202X
IS - 1
ER -