ACKR2: Nature's Decoy Receptor Lures Unsuspecting Chemokines in Psoriasis

Tomotaka Mabuchi, Samuel T Hwang

Research output: Contribution to journalComment/debate

4 Scopus citations

Abstract

While we know much about the processes mediated by the Th17 inflammatory pathway that is crucial in psoriasis, we actually know little about the processes by which most psoriatic patients maintain what grossly looks like non-inflamed, normal skin in the face of massive inflammatory changes in nearby affected skin. Other molecular regulators that defend the skin from global inflammation are likely to be involved, including molecules such as ACKR2, an atypical chemokine receptor whose role in psoriasiform dermatitis is explored by Shams et al.

Original languageEnglish (US)
Pages (from-to)7-11
Number of pages5
JournalJournal of Investigative Dermatology
Volume137
Issue number1
DOIs
StatePublished - Jan 1 2017

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ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Dermatology
  • Cell Biology

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