Abstract
Acetaminophen is a widely used analgesic that can cause acute liver failure when consumed above a maximum daily dose. Certain patients may be at increased risk of hepatocellular damage even at conventional therapeutic doses. We report a case of a 34-year-old man on carbamazepine for complex partial seizures who developed acute liver and renal failure on less than 2.5 grams a day of acetaminophen. This raises caution that patients on carbamazepine should avoid chronic use of acetaminophen, and if required use at lower doses with vigilant monitoring for signs of liver damage.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 329-332 |
| Number of pages | 4 |
| Journal | Epileptic Disorders |
| Volume | 11 |
| Issue number | 4 |
| DOIs | |
| State | Published - Dec 2009 |
| Externally published | Yes |
Keywords
- Acetaminophen toxicity
- Carbamazepine
- Epilepsy
- Liver failure
- Renal failure
ASJC Scopus subject areas
- Clinical Neurology
- Neurology
Fingerprint Dive into the research topics of 'Acetaminophen toxicity with concomitant use of carbamazepine'. Together they form a unique fingerprint.
Cite this
Jickling, G., Heino, A., & Ahmed, S. N. (2009). Acetaminophen toxicity with concomitant use of carbamazepine. Epileptic Disorders, 11(4), 329-332. https://doi.org/10.1684/epd.2009.0274