Accuracy of the thermodilution method in estimating high flow ‐ an in vitro study

K. A. Jarvis, M. J. Woliner, Eugene Steffey

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


The accuracy of thermodilution for measuring flow rates of 10–40 L/min was evaluated using a commercially available thermodilution cardiac output computer in an in vitro model. Water (36.5–37.5°C) was directed through a mixing chamber via a constant flow pump. Thermodilution estimates of flow using four different volumes (10, 20, 30, 40 ml) of iced water injectate were compared to simultaneous measurements of timed samples of effluent from the mixing chamber. Injectate volume had a significant impact on the accuracy of thermodilution estimation (p < 0.05). Thermodilution overestimated measured flow when 10 and 20 ml of injectate were used to determine flow rates < 20 L/min but underestimated flow when injectate volumes of 30 and 40 ml were used, or when measured flow was > 25 L/min. The discrepancy between thermodilution flow and measured flow increased as rate of fluid flow increased.

Original languageEnglish (US)
Pages (from-to)41-45
Number of pages5
JournalVeterinary Anaesthesia and Analgesia
Issue number1
StatePublished - Jan 1 1992

ASJC Scopus subject areas

  • veterinary(all)


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