Accuracy of pre-surgical fMRI confirmed by subsequent crossed aphasia

Paolo Vitali; Nina Dronkers; Alexander Pincherle; Anna Rita Giovagnoli; Carlo Marras; Ludovico D'Incerti; Francesco Ghielmetti; Roberto Spreafico; Flavio Villani

doi:10.1007/s10072-010-0426-y

Accuracy of pre-surgical fMRI confirmed by subsequent crossed aphasia

Paolo Vitali, Nina Dronkers, Alexander Pincherle, Anna Rita Giovagnoli, Carlo Marras, Ludovico D'Incerti, Francesco Ghielmetti, Roberto Spreafico, Flavio Villani

Neurology

Research output: Contribution to journal › Article

5 Scopus citations

Abstract

Atypical patterns of language activation in functional MRI (fMRI) are not unusual, particularly in patients with severe epilepsy. Still, the functional significance of these activations is under debate. We describe a case of a right-handed patient affected by drug-refractory right temporal lobe epilepsy in whom pre-surgical fMRI showed bilateral language activations, greater in the right hemisphere (RH). After surgery, a right subdural hematoma caused epileptic status and severe aphasia. This post-surgical complication of a crossed aphasia confirmed the prior fMRI findings of RH language thus stressing the value of pre-surgical fMRI evaluations, even when surgery is planned in the RH of a right-handed patient.

Original language	English (US)
Pages (from-to)	175-180
Number of pages	6
Journal	Neurological Sciences
Volume	32
Issue number	1
DOIs	https://doi.org/10.1007/s10072-010-0426-y
State	Published - Feb 2011

Keywords

Crossed aphasia
Functional MRI
Hemispheric dominance
Language
Temporal lobe epilepsy

ASJC Scopus subject areas

Clinical Neurology
Psychiatry and Mental health
Dermatology

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Vitali, P., Dronkers, N., Pincherle, A., Giovagnoli, A. R., Marras, C., D'Incerti, L., Ghielmetti, F., Spreafico, R., & Villani, F. (2011). Accuracy of pre-surgical fMRI confirmed by subsequent crossed aphasia. Neurological Sciences, 32(1), 175-180. https://doi.org/10.1007/s10072-010-0426-y

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