Accuracy and precision of in vitro volumetric measurements by three-dimensional sonography

Jonathan Wong, Eugenio O Gerscovich, Michael S. Cronan, J Anthony Seibert

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


RATIONALE AND OBJECTIVES. A radiologist often wishes to measure organ volume or monitor changes in internal lesion volume during treatment. If this can be determined via three-dimensional ultrasound, the relative simplicity of the procedure and the decreased cost and known risks to the patient would make this method an attractive alternative to other modalities. METHODS. Three-dimensional ultrasound scans were made of six phantoms: four nonechogenic spheres, one echogenic sphere, and one echogenic, irregularly shaped phantom. A total of 22 volume scans were produced. Volume estimations were made using data from cross-sectional areas and from linear measurements. In all, 193 volume estimations were made. These results were compared with known volumes and with volume estimates from computed tomography scans. RESULTS. Three-dimensional ultrasound detected size differences of 10% with 95% certainty. CONCLUSIONS. The accuracy and precision of volume estimates via three-dimensional ultrasound is at least as good as those obtained via conventional ultrasound.

Original languageEnglish (US)
Pages (from-to)26-29
Number of pages4
JournalInvestigative Radiology
Issue number1
StatePublished - Jan 1996


  • Instrument accuracy
  • Three-dimensional ultrasound
  • Ultrasonic diagnosis
  • Volume estimation

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology


Dive into the research topics of 'Accuracy and precision of in vitro volumetric measurements by three-dimensional sonography'. Together they form a unique fingerprint.

Cite this