Accumulation of natural killer cells after hepatic artery embolisation in the midgut carcinoid syndrome

B. Wangberg; H. Ahlman; Ulf Tylen; O. Nilsson; S. Hermodsson; K. Hellstrand

Accumulation of natural killer cells after hepatic artery embolisation in the midgut carcinoid syndrome

B. Wangberg, H. Ahlman, Ulf Tylen, O. Nilsson, S. Hermodsson, K. Hellstrand

Research output: Contribution to journal › Article › peer-review

Abstract

Eleven patients with disseminated midgut carcinoid tumour disease were subjected to hepatic artery embolisation. In six patients, lymphocytosis with a predominance of NK cells occurred and the cytotoxic activity of isolated lymphocytes increased. A relation between NK cell accumulation and subsequent radiological and biochemical response was observed, and it is suggested that anti-tumour mechanisms other than ischaemia may contribute to the therapeutic response in these patients.

Original language	English (US)
Pages (from-to)	617-618
Number of pages	2
Journal	British Journal of Cancer
Volume	71
Issue number	3
State	Published - 1995
Externally published	Yes

Keywords

Carcinoid tumours
Hepatic artery embolisation
NK cells

ASJC Scopus subject areas

Cancer Research
Oncology

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abstract = "Eleven patients with disseminated midgut carcinoid tumour disease were subjected to hepatic artery embolisation. In six patients, lymphocytosis with a predominance of NK cells occurred and the cytotoxic activity of isolated lymphocytes increased. A relation between NK cell accumulation and subsequent radiological and biochemical response was observed, and it is suggested that anti-tumour mechanisms other than ischaemia may contribute to the therapeutic response in these patients.",

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AU - Wangberg, B.

AU - Ahlman, H.

AU - Tylen, Ulf

AU - Nilsson, O.

AU - Hermodsson, S.

AU - Hellstrand, K.

PY - 1995

Y1 - 1995

N2 - Eleven patients with disseminated midgut carcinoid tumour disease were subjected to hepatic artery embolisation. In six patients, lymphocytosis with a predominance of NK cells occurred and the cytotoxic activity of isolated lymphocytes increased. A relation between NK cell accumulation and subsequent radiological and biochemical response was observed, and it is suggested that anti-tumour mechanisms other than ischaemia may contribute to the therapeutic response in these patients.

AB - Eleven patients with disseminated midgut carcinoid tumour disease were subjected to hepatic artery embolisation. In six patients, lymphocytosis with a predominance of NK cells occurred and the cytotoxic activity of isolated lymphocytes increased. A relation between NK cell accumulation and subsequent radiological and biochemical response was observed, and it is suggested that anti-tumour mechanisms other than ischaemia may contribute to the therapeutic response in these patients.

KW - Carcinoid tumours

KW - Hepatic artery embolisation

KW - NK cells

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ER -

Accumulation of natural killer cells after hepatic artery embolisation in the midgut carcinoid syndrome

Abstract

Keywords

ASJC Scopus subject areas

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