Accumulation of natural killer cells after hepatic artery embolisation in the midgut carcinoid syndrome

B. Wangberg, H. Ahlman, Ulf Tylen, O. Nilsson, S. Hermodsson, K. Hellstrand

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Abstract

Eleven patients with disseminated midgut carcinoid tumour disease were subjected to hepatic artery embolisation. In six patients, lymphocytosis with a predominance of NK cells occurred and the cytotoxic activity of isolated lymphocytes increased. A relation between NK cell accumulation and subsequent radiological and biochemical response was observed, and it is suggested that anti-tumour mechanisms other than ischaemia may contribute to the therapeutic response in these patients.

Original languageEnglish (US)
Pages (from-to)617-618
Number of pages2
JournalBritish Journal of Cancer
Volume71
Issue number3
StatePublished - 1995
Externally publishedYes

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Keywords

  • Carcinoid tumours
  • Hepatic artery embolisation
  • NK cells

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Wangberg, B., Ahlman, H., Tylen, U., Nilsson, O., Hermodsson, S., & Hellstrand, K. (1995). Accumulation of natural killer cells after hepatic artery embolisation in the midgut carcinoid syndrome. British Journal of Cancer, 71(3), 617-618.