Acceptability of a Rinse Screening Test for Diagnosing Head and Neck Squamous Cell Carcinoma Among Black Americans

Suzanne C. Lechner, Lutécia Pereira, Erika Reategui, Claudia Gordon, Margaret Byrne, Monica Webb Hooper, David J. Lee, Marianne Abouyared, Elizabeth Franzmann

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


OBJECTIVE: Head and neck squamous cell carcinoma (HNSCC) is a debilitating and deadly disease. We evaluated an easy-to-administer and innovative rinse that assays soluble CD44 and total protein as HNSCC early detection markers. We examined whether the rinse was acceptable and whether the results would promote screening behavior.

STUDY DESIGN: This is a prospective observational study.

METHODS: Participants (N = 150) from underserved, low-income Black American backgrounds completed assessments of satisfaction, intention to repeat test, and likely screening behavior after receiving results. Descriptive statistics, t tests, and analysis of variance (ANOVA) were conducted.

RESULTS: The rinse was highly acceptable to participants and perceived to be acceptable among peers. Participants strongly agreed that they would perform the rinse as prescribed, engage in preventative behaviors if results indicated risk of cancer, and initiate treatment if they had a positive cancer finding. Employed participants slightly disliked the taste of the rinse but were more likely to schedule a follow-up appointment and engage in preventative behaviors based on the results. Those with health-care coverage (including public health insurance) reported that the test was harder to perform than those who were uninsured.

CONCLUSION: An easy-to-use rinse technique is acceptable and likely to promote screening behavior among Black Americans at risk for HNSCC. Given that many cancer screening modalities are considered unpleasant to undergo, this rinse holds promise for promoting screening behaviors and, thereby, may result in early detection of this potentially fatal disease.IV.

Original languageEnglish (US)
Pages (from-to)62-67
Number of pages6
JournalJournal of Racial and Ethnic Health Disparities
Issue number1
StatePublished - Mar 1 2015
Externally publishedYes


  • Black Americans
  • Cancer screening
  • Head and neck cancer
  • Screening rinse

ASJC Scopus subject areas

  • Health(social science)
  • Anthropology
  • Sociology and Political Science
  • Health Policy
  • Public Health, Environmental and Occupational Health


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