Accelerator mass spectrometry for biomedical research

Karen Brown, Karen H. Dingley, Ken W Turteltaub

Research output: Contribution to journalArticlepeer-review

48 Scopus citations


Accelerator mass spectrometry (AMS) is the most sensitive method for detecting and quantifying rare long-lived isotopes with high precision. In this chapter, we review the principles underlying AMS-based biomedical studies, focusing on important practical considerations and experimental procedures needed for the detection and quantitation of 14C- and 3H-labeled compounds in various experiment types.

Original languageEnglish (US)
Article number14
Pages (from-to)423-443
Number of pages21
JournalMethods in Enzymology
StatePublished - 2005
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry


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