Abomasal interstitial fluid-to-blood concentration gradient of pepsinogen in calves with type-1 and type-2 ostertagiosis.

D. G. Baker, M. L. Bruss, Laurel J Gershwin

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Pepsinogen and protein concentrations were determined in blood samples, collected from the left gastroepiploic artery and vein, and in abomasal lymph from 15 steers naturally infected with Ostertagia ostertagi and 4 uninfected steers. In steers with type-1 ostertagiosis, the concentration gradient between the mucosal interstitium and the blood alone could account for higher than normal serum pepsinogen concentrations. High interstitial pepsinogen concentrations may have resulted from increased epithelial permeability or increased pepsinogen production and secretion. However, in steers with type-2 ostertagiosis, the concentration gradient could not entirely account for the high serum pepsinogen concentrations, suggesting that capillary permeability or surface area may have been altered. Lymphatic uptake contributed pepsinogen to the blood in all infected steers.

Original languageEnglish (US)
Pages (from-to)1294-1298
Number of pages5
JournalAmerican Journal of Veterinary Research
Volume54
Issue number8
StatePublished - Aug 1993

Fingerprint

Pepsinogen A
pepsinogen
extracellular fluids
Extracellular Fluid
calves
blood
blood serum
permeability
Gastroepiploic Artery
Ostertagia
Ostertagia ostertagi
lymph
Capillary Permeability
Lymph
Serum
arteries
Veins
Permeability
surface area
secretion

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Abomasal interstitial fluid-to-blood concentration gradient of pepsinogen in calves with type-1 and type-2 ostertagiosis. / Baker, D. G.; Bruss, M. L.; Gershwin, Laurel J.

In: American Journal of Veterinary Research, Vol. 54, No. 8, 08.1993, p. 1294-1298.

Research output: Contribution to journalArticle

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