Abnormal Pap smear follow-up in a high-risk population

L. P. Engelstad, Susan L Stewart, B. H. Nguyen, K. L. Bedeian, M. M. Rubin, R. J. Pasick, R. A. Hiatt

Research output: Contribution to journalArticle

56 Citations (Scopus)

Abstract

Low-income women are at high risk of developing cervical cancer attributable not only to the higher prevalence of risk factors in this population but also to the lack of timely follow-up of abnormal Pap smears. This study evaluates the efficacy of an aggressive follow-up strategy. Women with abnormal Pap smear results after screening in a public hospital emergency department were randomly assigned to follow-up either by a case-managed approach using computerized tracking and universal colposcopy or by traditional care. The main outcome was the proportion of women receiving follow-up in 6 months. A secondary outcome was the proportion of women receiving follow-up by 6 months and diagnostic resolution in 18 months. Of 54 women in the intervention group, 65% kept at least one follow-up appointment in 6 months compared with 41% of the 54 women in the control group (P = 0.012). Half the women in the intervention group versus 19% of women in the control group had follow-up in 6 months and diagnostic resolution in 18 months (P = 0.001). After adjusting for age, initial Pap smear result, and race/ethnicity, the odds of having follow-up in 6 months were four times greater for women in the intervention group (odds ratio = 4.0; 95% confidence interval, 1.6-9.7), and the odds of having both follow-up in 6 months and diagnostic resolution in 18 months were more than six times greater (odds ratio = 6.5; 95% confidence interval, 2.4-17.8). This study demonstrates that an aggressive follow-up strategy significantly improves the rate of both initial follow-up and diagnostic resolution of abnormal Pap smears among low-income women with atypical squamous cells of undetermined significance and atypical glandular cells of undetermined significance when compared with traditional care.

Original languageEnglish (US)
Pages (from-to)1015-1020
Number of pages6
JournalCancer Epidemiology Biomarkers and Prevention
Volume10
Issue number10
StatePublished - 2001
Externally publishedYes

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Papanicolaou Test
Population
Odds Ratio
Confidence Intervals
Colposcopy
Control Groups
Public Hospitals
Hospital Departments
Uterine Cervical Neoplasms
Hospital Emergency Service
Appointments and Schedules

ASJC Scopus subject areas

  • Epidemiology
  • Oncology

Cite this

Engelstad, L. P., Stewart, S. L., Nguyen, B. H., Bedeian, K. L., Rubin, M. M., Pasick, R. J., & Hiatt, R. A. (2001). Abnormal Pap smear follow-up in a high-risk population. Cancer Epidemiology Biomarkers and Prevention, 10(10), 1015-1020.

Abnormal Pap smear follow-up in a high-risk population. / Engelstad, L. P.; Stewart, Susan L; Nguyen, B. H.; Bedeian, K. L.; Rubin, M. M.; Pasick, R. J.; Hiatt, R. A.

In: Cancer Epidemiology Biomarkers and Prevention, Vol. 10, No. 10, 2001, p. 1015-1020.

Research output: Contribution to journalArticle

Engelstad, LP, Stewart, SL, Nguyen, BH, Bedeian, KL, Rubin, MM, Pasick, RJ & Hiatt, RA 2001, 'Abnormal Pap smear follow-up in a high-risk population', Cancer Epidemiology Biomarkers and Prevention, vol. 10, no. 10, pp. 1015-1020.
Engelstad LP, Stewart SL, Nguyen BH, Bedeian KL, Rubin MM, Pasick RJ et al. Abnormal Pap smear follow-up in a high-risk population. Cancer Epidemiology Biomarkers and Prevention. 2001;10(10):1015-1020.
Engelstad, L. P. ; Stewart, Susan L ; Nguyen, B. H. ; Bedeian, K. L. ; Rubin, M. M. ; Pasick, R. J. ; Hiatt, R. A. / Abnormal Pap smear follow-up in a high-risk population. In: Cancer Epidemiology Biomarkers and Prevention. 2001 ; Vol. 10, No. 10. pp. 1015-1020.
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