Abstract
The preparation of polyamine lipids via Michael addition of diamines to tetraester bisacrylates is described. A new pentaerythritol protection strategy enabled the synthesis of a bis(p-methoxybenzyl)diether diol which was used to prepare the saturated and unsaturated diester cores.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 8985-8988 |
| Number of pages | 4 |
| Journal | Tetrahedron Letters |
| Volume | 40 |
| Issue number | 51 |
| State | Published - Dec 17 1999 |
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ASJC Scopus subject areas
- Biochemistry
- Organic Chemistry
- Drug Discovery
Cite this
Lizarzaburu, M. E., Kurth, M. J., & Nantz, M. H. (1999). A versatile synthesis of tetraester polyamine lipids for gene transfection. Tetrahedron Letters, 40(51), 8985-8988.