Abstract
The preparation of polyamine lipids via Michael addition of diamines to tetraester bisacrylates is described. A new pentaerythritol protection strategy enabled the synthesis of a bis(p-methoxybenzyl)diether diol which was used to prepare the saturated and unsaturated diester cores.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 8985-8988 |
| Number of pages | 4 |
| Journal | Tetrahedron Letters |
| Volume | 40 |
| Issue number | 51 |
| State | Published - Dec 17 1999 |
Fingerprint
ASJC Scopus subject areas
- Biochemistry
- Organic Chemistry
- Drug Discovery
Cite this
A versatile synthesis of tetraester polyamine lipids for gene transfection. / Lizarzaburu, Mike E.; Kurth, Mark J.; Nantz, Michael H.
In: Tetrahedron Letters, Vol. 40, No. 51, 17.12.1999, p. 8985-8988.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A versatile synthesis of tetraester polyamine lipids for gene transfection
AU - Lizarzaburu, Mike E.
AU - Kurth, Mark J.
AU - Nantz, Michael H.
PY - 1999/12/17
Y1 - 1999/12/17
N2 - The preparation of polyamine lipids via Michael addition of diamines to tetraester bisacrylates is described. A new pentaerythritol protection strategy enabled the synthesis of a bis(p-methoxybenzyl)diether diol which was used to prepare the saturated and unsaturated diester cores.
AB - The preparation of polyamine lipids via Michael addition of diamines to tetraester bisacrylates is described. A new pentaerythritol protection strategy enabled the synthesis of a bis(p-methoxybenzyl)diether diol which was used to prepare the saturated and unsaturated diester cores.
UR - http://www.scopus.com/inward/record.url?scp=0033579645&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033579645&partnerID=8YFLogxK
M3 - Article
VL - 40
SP - 8985
EP - 8988
JO - Tetrahedron Letters
JF - Tetrahedron Letters
SN - 0040-4039
IS - 51
ER -