The preparation of polyamine lipids via Michael addition of diamines to tetraester bisacrylates is described. A new pentaerythritol protection strategy enabled the synthesis of a bis(p-methoxybenzyl)diether diol which was used to prepare the saturated and unsaturated diester cores.
|Original language||English (US)|
|Number of pages||4|
|State||Published - Dec 17 1999|
ASJC Scopus subject areas
- Organic Chemistry
- Drug Discovery