A unified discrete model of immune response

Debashish Chowdhury, Dietrich Stauffer, Prabhakara V Choudary

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

In this paper we propose a unified model of immune response in terms of discrete automata describing the concentrations of the cells constituting the immune network. The model of normal immune response proposed by Kaufman, Urbain and Thomas and that of auto-immune response proposed by Weisbuch, Atlan and Cohen are special cases of this unified model. Moreover, this model also describes the immune response in patients infected by the human immunodeficiency virus (HIV), the virus that is known to cause Acquired Immune Deficiency Syndrome (AIDS).

Original languageEnglish (US)
Pages (from-to)207-215
Number of pages9
JournalJournal of Theoretical Biology
Volume145
Issue number2
DOIs
StatePublished - Jul 24 1990
Externally publishedYes

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)
  • Applied Mathematics
  • Modeling and Simulation
  • Statistics and Probability
  • Medicine(all)

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