A technique for evaluating analgesia in conscious perching birds

Joanne R Paul-Murphy, David B. Brunson, Vjekoslav Miletic

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Objective - To develop a technique for objective assessment of modulation of nociperception in conscious perching birds. Animals - 31 adult African grey parrots. Procedure - Birds were randomly assigned to receive saline (0.9% NaCl) solution (n = 10), butorphanol tartrate (11), or buprenorphine hydrochloride (10), IM, Birds were fitted with a surface electrode on the medial metatarsus of 1 leg. An electrical stimulus was delivered to the bird's foot through an aluminum surface on half of the perch. The alternate side of the perch delivered a noxious thermal stimulus. A withdrawal response to either stimulus was recorded when the bird lifted its foot or vigorously flinched its wings. Results - Responses to thermal stimuli were extremely variable during baseline testing and after administration of drugs. Thus, significant differences were not detected after drug injection. In contrast, responses to an electrical stimulus were predictable with much less variation. Conclusions and Clinical Relevance - This method and device allowed for the reliable determination of withdrawal threshold in perching birds. Use of this technique for objective assessment of modulation of nociperception in conscious perching birds will enable assessment of analgesic drugs.

Original languageEnglish (US)
Pages (from-to)1213-1217
Number of pages5
JournalAmerican Journal of Veterinary Research
Volume60
Issue number10
StatePublished - Oct 1999
Externally publishedYes

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analgesia
Analgesia
Birds
birds
Perches
nociception
Nociception
perch
methodology
Foot
Hot Temperature
Metatarsus
Butorphanol
Parrots
drug injection
metatarsus
buprenorphine
heat
butorphanol
Buprenorphine

ASJC Scopus subject areas

  • veterinary(all)

Cite this

A technique for evaluating analgesia in conscious perching birds. / Paul-Murphy, Joanne R; Brunson, David B.; Miletic, Vjekoslav.

In: American Journal of Veterinary Research, Vol. 60, No. 10, 10.1999, p. 1213-1217.

Research output: Contribution to journalArticle

Paul-Murphy, Joanne R ; Brunson, David B. ; Miletic, Vjekoslav. / A technique for evaluating analgesia in conscious perching birds. In: American Journal of Veterinary Research. 1999 ; Vol. 60, No. 10. pp. 1213-1217.
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