A syndrome in commercial turkeys in California and Oregon characterized by a rear-limb necrotizing skeletal myopathy.

C. J. Cardona, A. A. Bickford, F. D. Galey, B. R. Charlton, G. Cooper

Research output: Contribution to journalArticle

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Abstract

A necrotizing skeletal myopathy of rear limbs was diagnosed in 17 flocks of commercial turkeys. The mean mortality attributed to the myopathy was 2.29% (range = 0.13-9.7%) over a mean period of 9.6 days (range = 6-14 days). The mean age of the birds at the time of onset was 7.4 weeks (range = 4-10.5 weeks). Clinically, birds experienced an episode of watery droppings and high-pitched crying, followed by rear-limb paresis or paralysis. Creatine kinase and aspartate aminotransferase were markedly elevated in birds with the myopathy. Grossly, a few birds had pale streaking in the muscles of the thighs and legs. Histologically, acute and subacute degeneration was present in myofibers of the legs, abdomen, thighs, back, and tail. The subacute lesion was characterized by marked sarcolemmal cell proliferation. Feed analyses ruled out selenium deficiency and the presence of mycotoxins as etiologies. Monensin was present in approved usage or only slightly elevated levels. A known potentiating antibiotic was being used concurrently with monensin in only one flock.

Original languageEnglish (US)
Pages (from-to)1092-1101
Number of pages10
JournalAvian Diseases
Volume36
Issue number4
StatePublished - Oct 1992

Fingerprint

muscular diseases
Muscular Diseases
limbs (animal)
Birds
Extremities
Monensin
monensin
birds
thighs
Thigh
Leg
legs
flocks
Crying
paresis
Mycotoxins
creatine kinase
Paresis
paralysis
Creatine Kinase

ASJC Scopus subject areas

  • Cancer Research
  • Immunology
  • veterinary(all)

Cite this

Cardona, C. J., Bickford, A. A., Galey, F. D., Charlton, B. R., & Cooper, G. (1992). A syndrome in commercial turkeys in California and Oregon characterized by a rear-limb necrotizing skeletal myopathy. Avian Diseases, 36(4), 1092-1101.

A syndrome in commercial turkeys in California and Oregon characterized by a rear-limb necrotizing skeletal myopathy. / Cardona, C. J.; Bickford, A. A.; Galey, F. D.; Charlton, B. R.; Cooper, G.

In: Avian Diseases, Vol. 36, No. 4, 10.1992, p. 1092-1101.

Research output: Contribution to journalArticle

Cardona, CJ, Bickford, AA, Galey, FD, Charlton, BR & Cooper, G 1992, 'A syndrome in commercial turkeys in California and Oregon characterized by a rear-limb necrotizing skeletal myopathy.', Avian Diseases, vol. 36, no. 4, pp. 1092-1101.
Cardona, C. J. ; Bickford, A. A. ; Galey, F. D. ; Charlton, B. R. ; Cooper, G. / A syndrome in commercial turkeys in California and Oregon characterized by a rear-limb necrotizing skeletal myopathy. In: Avian Diseases. 1992 ; Vol. 36, No. 4. pp. 1092-1101.
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