A study of twelve Southern California communities with differing levels and types of air pollution

I. Prevalence of respiratory morbidity

John M. Peters, Edward Avol, William Navidi, Stephanie J. London, W. James Gauderman, Fred Lurmann, William S. Linn, Helene G Margolis, Edward Rappaport, Henry Gong, Duncan C. Thomas

Research output: Contribution to journalArticle

284 Citations (Scopus)

Abstract

To study possible chronic respiratory effects of air pollutants, we initiated a 10-yr prospective cohort study of Southern California children, with a study design focused on four pollutants: ozone, particulate matter, acids, and nitrogen dioxide (NO2). Twelve demographically similar communities were selected on the basis of historic monitoring information to represent extremes of exposure to one or more pollutants. In each community, about 150 public school students in grade 4, 75 in grade 7, and 75 in grade 10 were enrolled through their classrooms. Informed consent and written responses to surveys about students' lifetime residential histories, historic and current health status, residential characteristics, and physical activity were obtained with the help of the parents. In the first testing season, 3,676 students returned questionnaires. We confirmed associations previously reported between respiratory morbidity prevalence and the presence of personal, demographic, and residential risk factors. Rates of respiratory illness were higher for males, those living in houses with pets, pests, mildew, and water damage, those whose parents had asthma, and those living In houses with smokers. Wheeze prevalence was positively associated with levels of both acid (odds ratio [OR] = 1.45; 95% confidence interval [CI], 1.14- 1.83) and NO2 (OR = 1.54; 95% CI, 1.08-2.19) in boys. We conclude, based on this cross-sectional assessment of questionnaire responses, that current levels of ambient air pollution in Southern California may be associated with effects on schoolchildren's respiratory morbidity as assessed by questionnaire.

Original languageEnglish (US)
Pages (from-to)760-767
Number of pages8
JournalAmerican Journal of Respiratory and Critical Care Medicine
Volume159
Issue number3
StatePublished - 1999

Fingerprint

Air Pollution
Morbidity
Students
Parents
Odds Ratio
Confidence Intervals
Nitrogen Dioxide
Air Pollutants
Acids
Particulate Matter
Ozone
Pets
Respiratory Rate
Informed Consent
Health Status
Cohort Studies
Asthma
Demography
Prospective Studies
Exercise

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

A study of twelve Southern California communities with differing levels and types of air pollution : I. Prevalence of respiratory morbidity. / Peters, John M.; Avol, Edward; Navidi, William; London, Stephanie J.; Gauderman, W. James; Lurmann, Fred; Linn, William S.; Margolis, Helene G; Rappaport, Edward; Gong, Henry; Thomas, Duncan C.

In: American Journal of Respiratory and Critical Care Medicine, Vol. 159, No. 3, 1999, p. 760-767.

Research output: Contribution to journalArticle

Peters, JM, Avol, E, Navidi, W, London, SJ, Gauderman, WJ, Lurmann, F, Linn, WS, Margolis, HG, Rappaport, E, Gong, H & Thomas, DC 1999, 'A study of twelve Southern California communities with differing levels and types of air pollution: I. Prevalence of respiratory morbidity', American Journal of Respiratory and Critical Care Medicine, vol. 159, no. 3, pp. 760-767.
Peters, John M. ; Avol, Edward ; Navidi, William ; London, Stephanie J. ; Gauderman, W. James ; Lurmann, Fred ; Linn, William S. ; Margolis, Helene G ; Rappaport, Edward ; Gong, Henry ; Thomas, Duncan C. / A study of twelve Southern California communities with differing levels and types of air pollution : I. Prevalence of respiratory morbidity. In: American Journal of Respiratory and Critical Care Medicine. 1999 ; Vol. 159, No. 3. pp. 760-767.
@article{2d3e27f6902d4b0fb41173d5f888e421,
title = "A study of twelve Southern California communities with differing levels and types of air pollution: I. Prevalence of respiratory morbidity",
abstract = "To study possible chronic respiratory effects of air pollutants, we initiated a 10-yr prospective cohort study of Southern California children, with a study design focused on four pollutants: ozone, particulate matter, acids, and nitrogen dioxide (NO2). Twelve demographically similar communities were selected on the basis of historic monitoring information to represent extremes of exposure to one or more pollutants. In each community, about 150 public school students in grade 4, 75 in grade 7, and 75 in grade 10 were enrolled through their classrooms. Informed consent and written responses to surveys about students' lifetime residential histories, historic and current health status, residential characteristics, and physical activity were obtained with the help of the parents. In the first testing season, 3,676 students returned questionnaires. We confirmed associations previously reported between respiratory morbidity prevalence and the presence of personal, demographic, and residential risk factors. Rates of respiratory illness were higher for males, those living in houses with pets, pests, mildew, and water damage, those whose parents had asthma, and those living In houses with smokers. Wheeze prevalence was positively associated with levels of both acid (odds ratio [OR] = 1.45; 95{\%} confidence interval [CI], 1.14- 1.83) and NO2 (OR = 1.54; 95{\%} CI, 1.08-2.19) in boys. We conclude, based on this cross-sectional assessment of questionnaire responses, that current levels of ambient air pollution in Southern California may be associated with effects on schoolchildren's respiratory morbidity as assessed by questionnaire.",
author = "Peters, {John M.} and Edward Avol and William Navidi and London, {Stephanie J.} and Gauderman, {W. James} and Fred Lurmann and Linn, {William S.} and Margolis, {Helene G} and Edward Rappaport and Henry Gong and Thomas, {Duncan C.}",
year = "1999",
language = "English (US)",
volume = "159",
pages = "760--767",
journal = "American Journal of Respiratory and Critical Care Medicine",
issn = "1073-449X",
publisher = "American Thoracic Society",
number = "3",

}

TY - JOUR

T1 - A study of twelve Southern California communities with differing levels and types of air pollution

T2 - I. Prevalence of respiratory morbidity

AU - Peters, John M.

AU - Avol, Edward

AU - Navidi, William

AU - London, Stephanie J.

AU - Gauderman, W. James

AU - Lurmann, Fred

AU - Linn, William S.

AU - Margolis, Helene G

AU - Rappaport, Edward

AU - Gong, Henry

AU - Thomas, Duncan C.

PY - 1999

Y1 - 1999

N2 - To study possible chronic respiratory effects of air pollutants, we initiated a 10-yr prospective cohort study of Southern California children, with a study design focused on four pollutants: ozone, particulate matter, acids, and nitrogen dioxide (NO2). Twelve demographically similar communities were selected on the basis of historic monitoring information to represent extremes of exposure to one or more pollutants. In each community, about 150 public school students in grade 4, 75 in grade 7, and 75 in grade 10 were enrolled through their classrooms. Informed consent and written responses to surveys about students' lifetime residential histories, historic and current health status, residential characteristics, and physical activity were obtained with the help of the parents. In the first testing season, 3,676 students returned questionnaires. We confirmed associations previously reported between respiratory morbidity prevalence and the presence of personal, demographic, and residential risk factors. Rates of respiratory illness were higher for males, those living in houses with pets, pests, mildew, and water damage, those whose parents had asthma, and those living In houses with smokers. Wheeze prevalence was positively associated with levels of both acid (odds ratio [OR] = 1.45; 95% confidence interval [CI], 1.14- 1.83) and NO2 (OR = 1.54; 95% CI, 1.08-2.19) in boys. We conclude, based on this cross-sectional assessment of questionnaire responses, that current levels of ambient air pollution in Southern California may be associated with effects on schoolchildren's respiratory morbidity as assessed by questionnaire.

AB - To study possible chronic respiratory effects of air pollutants, we initiated a 10-yr prospective cohort study of Southern California children, with a study design focused on four pollutants: ozone, particulate matter, acids, and nitrogen dioxide (NO2). Twelve demographically similar communities were selected on the basis of historic monitoring information to represent extremes of exposure to one or more pollutants. In each community, about 150 public school students in grade 4, 75 in grade 7, and 75 in grade 10 were enrolled through their classrooms. Informed consent and written responses to surveys about students' lifetime residential histories, historic and current health status, residential characteristics, and physical activity were obtained with the help of the parents. In the first testing season, 3,676 students returned questionnaires. We confirmed associations previously reported between respiratory morbidity prevalence and the presence of personal, demographic, and residential risk factors. Rates of respiratory illness were higher for males, those living in houses with pets, pests, mildew, and water damage, those whose parents had asthma, and those living In houses with smokers. Wheeze prevalence was positively associated with levels of both acid (odds ratio [OR] = 1.45; 95% confidence interval [CI], 1.14- 1.83) and NO2 (OR = 1.54; 95% CI, 1.08-2.19) in boys. We conclude, based on this cross-sectional assessment of questionnaire responses, that current levels of ambient air pollution in Southern California may be associated with effects on schoolchildren's respiratory morbidity as assessed by questionnaire.

UR - http://www.scopus.com/inward/record.url?scp=0033059557&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033059557&partnerID=8YFLogxK

M3 - Article

VL - 159

SP - 760

EP - 767

JO - American Journal of Respiratory and Critical Care Medicine

JF - American Journal of Respiratory and Critical Care Medicine

SN - 1073-449X

IS - 3

ER -