A study of some pathogenetic aspects of bovine viral diarrhea virus infection.

G. Castrucci, F. Frigeri, Bennie Osburn, M. Ferrari, M. M. Sawyer, V. Aldrovandi

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

The cytopathic (CP) strain TVM-2 of bovine virus diarrhea virus (BVDV) induced in calves a severe disease, whereas the calves inoculated with the non-cytopathic (NCP) New York-1 strain, remained clinically normal. When calves were immunosuppressed with dexamethasone (DMS) they underwent an overt, generally fatal disease. This result was obtained with either the CP and the NCP strain of BVDV. It was speculated that the immunosuppressive activity of BVDV could be a property peculiar to certain isolates of the virus.

Original languageEnglish (US)
Pages (from-to)101-108
Number of pages8
JournalArchives of virology. Supplementum
Volume3
StatePublished - Dec 1 1991
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Microbiology(all)

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