A study of nerve regeneration and neuroma formation after nerve suture by various techniques

F. W. Bora, David E Pleasure, N. A. Didizian

Research output: Contribution to journalArticle

68 Scopus citations


The effectiveness of epineurial, perineurial, and a combined epiperineurial method of nerve suture in the severed sciatic nerve of rabbits was studied by biochemical assay of the collagen just distal to the neuroma and the collagen and myelin content of the posterior tibial nerve. Repairs were done both immediately after severance and in a separate group 3 weeks later. More collagen was found near the neuroma in the immediate epineurial group, but 60 percent of the normal myelin was found in the posterior tibial nerve after the immediate epineurial suture compared to 28.3 percent in the immediate perineurial group.

Original languageEnglish (US)
Pages (from-to)138-143
Number of pages6
JournalJournal of Hand Surgery
Issue number2
StatePublished - 1976
Externally publishedYes


ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Surgery

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