A simple approach to performing quantitative cancer risk assessment using published results from occupational epidemiology studies

Edwin Van Wijngaarden, Irva Hertz-Picciotto

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Quantitative risk assessment provides formalized scientific input for setting occupational and environmental standards for potentially toxic exposures. We describe the methods to perform quantitative cancer risk assessment based on published epidemiological literature using a hand calculator or spreadsheet. These methods are illustrated for some suspected or known human carcinogens, including perchloroethylene, formaldehyde, benzene and nickel. The approach to cancer risk assessment presented here may prove useful for those without access to original data from epidemiologic studies. The methods described should facilitate the use of published epidemiological data in the estimation of cancer risk in the general or working population.

Original languageEnglish (US)
Pages (from-to)81-87
Number of pages7
JournalScience of the Total Environment
Volume332
Issue number1-3
DOIs
Publication statusPublished - Oct 1 2004

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Keywords

  • Cancer
  • Occupational epidemiology
  • Risk assessment
  • Statistical methods

ASJC Scopus subject areas

  • Environmental Chemistry
  • Environmental Science(all)

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