A Salmonella frameshift suppressor that acts at runs of a residues in the messenger RNA

Tadahiko Kohno, John R. Roth

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

A Salmonella mutation is described that suppresses + 1 frameshift mutations in runs of A residues in the messenger RNA. The suppressor mutation is dominant and maps very close to the nag locus at minute 15 of the Salmonella chromosome. A lysine transfer RNA is known to map very close to this position. Since the frameshift suppressor appears allelic to a nonsense suppressor (UA(A/G)), it seems likely that the suppressor will prove to affect lysine tRNA (AA(A/G)).

Original languageEnglish (US)
Pages (from-to)37-52
Number of pages16
JournalJournal of Molecular Biology
Volume126
Issue number1
DOIs
StatePublished - Nov 25 1978

ASJC Scopus subject areas

  • Virology

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