A Salmonella frameshift suppressor that acts at runs of a residues in the messenger RNA

Tadahiko Kohno, John R. Roth

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

A Salmonella mutation is described that suppresses + 1 frameshift mutations in runs of A residues in the messenger RNA. The suppressor mutation is dominant and maps very close to the nag locus at minute 15 of the Salmonella chromosome. A lysine transfer RNA is known to map very close to this position. Since the frameshift suppressor appears allelic to a nonsense suppressor (UA(A/G)), it seems likely that the suppressor will prove to affect lysine tRNA (AA(A/G)).

Original languageEnglish (US)
Pages (from-to)37-52
Number of pages16
JournalJournal of Molecular Biology
Volume126
Issue number1
DOIs
StatePublished - Nov 25 1978

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Transfer RNA
Salmonella
Lysine
Genetic Suppression
Chromosomes, Human, Pair 15
Messenger RNA
Frameshift Mutation
Mutation

ASJC Scopus subject areas

  • Virology

Cite this

A Salmonella frameshift suppressor that acts at runs of a residues in the messenger RNA. / Kohno, Tadahiko; Roth, John R.

In: Journal of Molecular Biology, Vol. 126, No. 1, 25.11.1978, p. 37-52.

Research output: Contribution to journalArticle

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