TY - JOUR
T1 - A review of highly pathogenic avian influenza in birds, with an emphasis on asian H5N1 and recommendations for prevention and control
AU - Kelly, Terra R.
AU - Hawkins, Michelle
AU - Sandrock, Christian E
AU - Boyce, Walter M
PY - 2008/3
Y1 - 2008/3
N2 - Avian influenza is a disease of both veterinary and public health importance. Influenza A viruses infect a range of hosts, including humans, and can cause significant morbidity and mortality. These viruses have high genetic variability, and new strains develop through both mutation and reassortment. Modes of transmission as well as the location of viral shedding may differ both by host species and by viral strain. Clinical signs of influenza A virus infection in birds vary considerably depending on the viral subtype, environmental factors, and age, health status, and species of the bird and range from decreased egg production and gastrointestinal manifestations to nervous system disorders and respiratory signs. Most commonly, peracute death with minimal clinical disease is observed in poultry infected with a highly pathogenic avian influenza virus. There are various prevention and control strategies for avian influenza, including education, biosecurity, surveillance, culling of infected animals, and vaccination. These strategies will differ by institution and current federal regulations. Each institution should have an established biosecurity protocol that can be properly instituted. Lastly, human health precautions, such as proper hand hygiene, personal protective equipment, and employee health monitoring, are imperative for at-risk individuals.
AB - Avian influenza is a disease of both veterinary and public health importance. Influenza A viruses infect a range of hosts, including humans, and can cause significant morbidity and mortality. These viruses have high genetic variability, and new strains develop through both mutation and reassortment. Modes of transmission as well as the location of viral shedding may differ both by host species and by viral strain. Clinical signs of influenza A virus infection in birds vary considerably depending on the viral subtype, environmental factors, and age, health status, and species of the bird and range from decreased egg production and gastrointestinal manifestations to nervous system disorders and respiratory signs. Most commonly, peracute death with minimal clinical disease is observed in poultry infected with a highly pathogenic avian influenza virus. There are various prevention and control strategies for avian influenza, including education, biosecurity, surveillance, culling of infected animals, and vaccination. These strategies will differ by institution and current federal regulations. Each institution should have an established biosecurity protocol that can be properly instituted. Lastly, human health precautions, such as proper hand hygiene, personal protective equipment, and employee health monitoring, are imperative for at-risk individuals.
KW - Avian
KW - Avian influenza
KW - H5N1
KW - Highly pathogenic avian influenza
KW - Influenza A
KW - Orthomyxoviridae
UR - http://www.scopus.com/inward/record.url?scp=44449116140&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=44449116140&partnerID=8YFLogxK
U2 - 10.1647/2006-036R.1
DO - 10.1647/2006-036R.1
M3 - Article
C2 - 18543597
AN - SCOPUS:44449116140
VL - 22
SP - 1
EP - 16
JO - Journal of Avian Medicine and Surgery
JF - Journal of Avian Medicine and Surgery
SN - 1082-6742
IS - 1
ER -