A retrospective study of cutaneous equine sarcoidosis and its potential infectious aetiological agents

Ian B. Spiegel, Stephen D White, Janet E Foley, Nicole L. Drazenovich, Peter J. Ihrke, Verena K Affolter

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

Nine horses from ages 5 to 21 years were diagnosed with cutaneous equine sarcoidosis (ES) over an 18-year period. In addition to skin, the lungs were frequently involved, with other organ systems affected less commonly. A predisposition for thoroughbreds and geldings was noted. Cutaneous lesions and signs included crusts, scales, alopecia and pruritus. These were found at various sites, particularly the legs/thighs/elbows, thorax, neck, face and ventral abdomen. Three horses were euthanized shortly after hospitalization; others survived as long as 12 years. Histopathologic stains, immunohistochemistry and polymerase chain reaction assays on paraffin-embedded cutaneous specimens from eight horses for Mycobacterium spp., Coccidioides immitis, Cryptococcus neoformans, Corynebacterium pseudotuberculosis, and Borrelia burgdorferi were all negative. The aetiology of ES is unlikely microbial and continues to be a diagnosis of exclusion. ES, when limited to the skin, is associated with a good prognosis, with either partial or complete response to glucocorticoid therapy in all the surviving horses.

Original languageEnglish (US)
Pages (from-to)51-62
Number of pages12
JournalVeterinary Dermatology
Volume17
Issue number1
DOIs
StatePublished - Feb 2006

ASJC Scopus subject areas

  • veterinary(all)

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