A rapid technique for producing ethanol dependence in the rat

Dale S. Cannon; Timothy B. Baker; Robert F Berman; Carol A. Atkinson

doi:10.1016/0091-3057(74)90117-8

A rapid technique for producing ethanol dependence in the rat

Dale S. Cannon, Timothy B. Baker, Robert F Berman, Carol A. Atkinson

Research output: Contribution to journal › Article

18 Scopus citations

Abstract

Ethanol dependence in the rat is demonstrated following 2-4 days of intragastric intubation with 8-12 g/kg/day. Withdrawal symptoms include tremulousness, hyperactivity, and seizures. Nutritional deficiency is shown to be an insufficient explanation of the withdrawal symptoms produced.

Original language	English (US)
Pages (from-to)	831-834
Number of pages	4
Journal	Pharmacology, Biochemistry and Behavior
Volume	2
Issue number	6
DOIs	https://doi.org/10.1016/0091-3057(74)90117-8
State	Published - 1974
Externally published	Yes

Keywords

Dependence
Ethanol
Rat
Seizures

ASJC Scopus subject areas

Biochemistry
Behavioral Neuroscience
Pharmacology

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10.1016/0091-3057(74)90117-8

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Cannon, D. S., Baker, T. B., Berman, R. F., & Atkinson, C. A. (1974). A rapid technique for producing ethanol dependence in the rat. Pharmacology, Biochemistry and Behavior, 2(6), 831-834. https://doi.org/10.1016/0091-3057(74)90117-8

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abstract = "Ethanol dependence in the rat is demonstrated following 2-4 days of intragastric intubation with 8-12 g/kg/day. Withdrawal symptoms include tremulousness, hyperactivity, and seizures. Nutritional deficiency is shown to be an insufficient explanation of the withdrawal symptoms produced.",

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AU - Baker, Timothy B.

AU - Berman, Robert F

AU - Atkinson, Carol A.

PY - 1974

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N2 - Ethanol dependence in the rat is demonstrated following 2-4 days of intragastric intubation with 8-12 g/kg/day. Withdrawal symptoms include tremulousness, hyperactivity, and seizures. Nutritional deficiency is shown to be an insufficient explanation of the withdrawal symptoms produced.

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KW - Dependence

KW - Ethanol

KW - Rat

KW - Seizures

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