Abstract
A treatment planning program for radioimmunotherapy employing quantitative Anger camera imaging and the MIRD formalism has been designed and implemented on a clinical nuclear medicine computer. Radionuclide residence times are calculated from linear, mono- and bi-exponential, and cubic spline fits to regional activity versus time curves, and radiation-absorbed dose estimates for all target organs for 131I, 67Cu, and 58 other radionuclides can be calculated. This software has been successfully applied to radioimmunotherapy of B-cell malignancies and breast adenocarcinomas.
Original language | English (US) |
---|---|
Pages (from-to) | 525-532 |
Number of pages | 8 |
Journal | Nuclear Medicine and Biology |
Volume | 23 |
Issue number | 4 |
DOIs | |
State | Published - May 1996 |
Keywords
- Dosimetry
- MIRD
- Monoclonal antibodies
- Radioimmunoimaging
- Radioimmunotherapy
- Treatment planning
ASJC Scopus subject areas
- Molecular Medicine
- Radiology Nuclear Medicine and imaging
- Cancer Research