A prospective, double-blind, randomized study of the effects of perioperative steroids on palatoplasty patients

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Objective: To determine whether perioperative steroids affect the outcome of patients who undergo palatoplasty. Design: A prospective, double-blind, randomized study. Setting: A university medical center. Patients: Twenty patients undergoing primary repair of a cleft palate. Intervention: A prospective double-blind technique was used to randomly assign patients to receive a placebo or dexamethasone sodium phosphate perioperatively. Main Outcome Measures: Patients were monitored for postoperative airway distress, fever, oral fluid intake, days of hospitalization, and wound healing. Results: The use of perioperative steroids was associated with shorter hospitalizations. No adverse sequelae from the administration of steroids were identified. Conclusion: In our current managed care environment, the use of perioperative steroids may play an important role in reducing health care costs.

Original languageEnglish (US)
Pages (from-to)267-270
Number of pages4
JournalArchives of Otolaryngology - Head and Neck Surgery
Issue number3
StatePublished - Mar 1996


ASJC Scopus subject areas

  • Otorhinolaryngology

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