A preliminary study of the neuropsychological heterogeneity of familial schizophrenia

Frederic J. Sautter; Barbara E McDermott; John Cornwell; Janet Johnson; Alicia Borges; Alexander F. Wilson; Jennifer J. Vasterling; Anne L. Foundas

doi:10.1016/0920-9964(95)00015-1

A preliminary study of the neuropsychological heterogeneity of familial schizophrenia

Frederic J. Sautter, Barbara E McDermott, John Cornwell, Janet Johnson, Alicia Borges, Alexander F. Wilson, Jennifer J. Vasterling, Anne L. Foundas

Research output: Contribution to journal › Article

14 Scopus citations

Abstract

This exploratory study describes the heterogeneity of the neuropsychological deficits that characterize familial schizophrenia. Forty-six familial schizophrenics showed significantly more variability in abstraction and problem-solving and motor control than 39 non-familial schizophrenics. Cluster analyses of these two neuropsychological parameters indicate that while the non-familial schizophrenics fall into one homogeneous cluster, the familial schizophrenics fall into three relatively distinct clusters which differ significantly in their morbid risk for schizophrenic-spectrum disorder. These preliminary data suggest that frontal lobe deficits are associated with an increased familial risk for schizophrenia.

Original language	English (US)
Pages (from-to)	1-7
Number of pages	7
Journal	Schizophrenia Research
Volume	18
Issue number	1
DOIs	https://doi.org/10.1016/0920-9964(95)00015-1
State	Published - 1995
Externally published	Yes

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Keywords

(Schizophrenia)
Family history
Genetics
Heterogeneity
Neuropsychology

ASJC Scopus subject areas

Psychiatry and Mental health
Biological Psychiatry
Behavioral Neuroscience
Neurology
Psychology(all)

Cite this

Sautter, F. J., McDermott, B. E., Cornwell, J., Johnson, J., Borges, A., Wilson, A. F., Vasterling, J. J., & Foundas, A. L. (1995). A preliminary study of the neuropsychological heterogeneity of familial schizophrenia. Schizophrenia Research, 18(1), 1-7. https://doi.org/10.1016/0920-9964(95)00015-1

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AU - Wilson, Alexander F.

AU - Vasterling, Jennifer J.

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10.1016/0920-9964(95)00015-1