A preliminary study of the neuropsychological heterogeneity of familial schizophrenia

Frederic J. Sautter; Barbara E McDermott; John Cornwell; Janet Johnson; Alicia Borges; Alexander F. Wilson; Jennifer J. Vasterling; Anne L. Foundas

doi:10.1016/0920-9964(95)00015-1

A preliminary study of the neuropsychological heterogeneity of familial schizophrenia

Frederic J. Sautter, Barbara E McDermott, John Cornwell, Janet Johnson, Alicia Borges, Alexander F. Wilson, Jennifer J. Vasterling, Anne L. Foundas

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

This exploratory study describes the heterogeneity of the neuropsychological deficits that characterize familial schizophrenia. Forty-six familial schizophrenics showed significantly more variability in abstraction and problem-solving and motor control than 39 non-familial schizophrenics. Cluster analyses of these two neuropsychological parameters indicate that while the non-familial schizophrenics fall into one homogeneous cluster, the familial schizophrenics fall into three relatively distinct clusters which differ significantly in their morbid risk for schizophrenic-spectrum disorder. These preliminary data suggest that frontal lobe deficits are associated with an increased familial risk for schizophrenia.

Original language	English (US)
Pages (from-to)	1-7
Number of pages	7
Journal	Schizophrenia Research
Volume	18
Issue number	1
DOIs	https://doi.org/10.1016/0920-9964(95)00015-1
State	Published - 1995
Externally published	Yes

Keywords

(Schizophrenia)
Family history
Genetics
Heterogeneity
Neuropsychology

ASJC Scopus subject areas

Psychiatry and Mental health
Biological Psychiatry
Behavioral Neuroscience
Neurology
Psychology(all)

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10.1016/0920-9964(95)00015-1

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A preliminary study of the neuropsychological heterogeneity of familial schizophrenia. / Sautter, Frederic J.; McDermott, Barbara E; Cornwell, John; Johnson, Janet; Borges, Alicia; Wilson, Alexander F.; Vasterling, Jennifer J.; Foundas, Anne L.

In: Schizophrenia Research, Vol. 18, No. 1, 1995, p. 1-7.

Research output: Contribution to journal › Article › peer-review

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AU - Wilson, Alexander F.

AU - Vasterling, Jennifer J.

AU - Foundas, Anne L.

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KW - Genetics

KW - Heterogeneity

KW - Neuropsychology

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A preliminary study of the neuropsychological heterogeneity of familial schizophrenia

Abstract

Keywords

ASJC Scopus subject areas

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