Abstract
This exploratory study describes the heterogeneity of the neuropsychological deficits that characterize familial schizophrenia. Forty-six familial schizophrenics showed significantly more variability in abstraction and problem-solving and motor control than 39 non-familial schizophrenics. Cluster analyses of these two neuropsychological parameters indicate that while the non-familial schizophrenics fall into one homogeneous cluster, the familial schizophrenics fall into three relatively distinct clusters which differ significantly in their morbid risk for schizophrenic-spectrum disorder. These preliminary data suggest that frontal lobe deficits are associated with an increased familial risk for schizophrenia.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1-7 |
| Number of pages | 7 |
| Journal | Schizophrenia Research |
| Volume | 18 |
| Issue number | 1 |
| DOIs | |
| State | Published - 1995 |
| Externally published | Yes |
Keywords
- (Schizophrenia)
- Family history
- Genetics
- Heterogeneity
- Neuropsychology
ASJC Scopus subject areas
- Psychiatry and Mental health
- Biological Psychiatry
- Behavioral Neuroscience
- Neurology
- Psychology(all)
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Cite this
Sautter, F. J., McDermott, B. E., Cornwell, J., Johnson, J., Borges, A., Wilson, A. F., Vasterling, J. J., & Foundas, A. L. (1995). A preliminary study of the neuropsychological heterogeneity of familial schizophrenia. Schizophrenia Research, 18(1), 1-7. https://doi.org/10.1016/0920-9964(95)00015-1