Abstract
This exploratory study describes the heterogeneity of the neuropsychological deficits that characterize familial schizophrenia. Forty-six familial schizophrenics showed significantly more variability in abstraction and problem-solving and motor control than 39 non-familial schizophrenics. Cluster analyses of these two neuropsychological parameters indicate that while the non-familial schizophrenics fall into one homogeneous cluster, the familial schizophrenics fall into three relatively distinct clusters which differ significantly in their morbid risk for schizophrenic-spectrum disorder. These preliminary data suggest that frontal lobe deficits are associated with an increased familial risk for schizophrenia.
Original language | English (US) |
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Pages (from-to) | 1-7 |
Number of pages | 7 |
Journal | Schizophrenia Research |
Volume | 18 |
Issue number | 1 |
DOIs | |
State | Published - 1995 |
Externally published | Yes |
Keywords
- (Schizophrenia)
- Family history
- Genetics
- Heterogeneity
- Neuropsychology
ASJC Scopus subject areas
- Psychiatry and Mental health
- Biological Psychiatry
- Behavioral Neuroscience
- Neurology
- Psychology(all)