A potent juvenile hormone mimic, 1-(4′-ethylphenoxy)-6,7-epoxy-3,7-dimethyl-2-octene, labeled with tritium in either the ethylphenyl- or geranyl-derived moiety

Hideo Kamimura, Bruce D. Hammock, Izuru Yamamoto, John E. Casida

Research output: Contribution to journalArticle

10 Scopus citations


Reduction of citral with sodium borotritide, conversion of the alcohol product to the bromo derivative, formation of the ether by reaction with 4-ethyl-phenol, and epoxidation yields 1-(4′-ethylphenoxy)-6,7 - epoxy - 3,7 - dimethyl - 2 - octene-1 -3H. Alternatively, tritiation of 4-ethylphenol with tritium water in sulfuric acid, reaction of the recovered phenol with geranyl bromide, and epoxidation yields 1 - (4′-ethylphen-3H-oxy)-6,7-epoxy-3,7-dimethyl-2-octene. the products have a high specific activity (33 to 654 mCi per mmol) and are useful in studies on the degradation and mode of action of this potent juvenile hormone mimic.

Original languageEnglish (US)
Pages (from-to)439-442
Number of pages4
JournalJournal of Agricultural and Food Chemistry
Issue number2
StatePublished - 1972
Externally publishedYes


ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • Food Science
  • Chemistry (miscellaneous)

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